PILOT STUDY ON THE EFFECTIVENESS OF CHOLINE ALFOSCERATE IN THE UNDER THRESHOLD DEPRESSION OF THE ELDERLY
Key facts
- Where
- Lodi, OlaszországSee the site
- Phase
- 4. fázis
Where in Olaszország
- Azienda Socio Sanitaria Territoriale di LodiLodi, OlaszországTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Azienda Socio Sanitaria Territoriale Di Lodi
- Trial code
- EU 2025-520899-25-00
- Record updated
- 2025. augusztus 22.
- Original description
The primary objective of the study is to evaluate the efficacy of choline alfoscerate on subthreshold depression in elderly patients.Read full original descriptionShow less
The primary objective of the study is to evaluate the efficacy of choline alfoscerate on subthreshold depression in elderly patients.
Inclusion: Age = 65 years 2. From 2 to 4 depressive symptoms present for at least two weeks prior to enrollment (Judd et al., 1994) 3. Mini-Mental State Examination (MMSE) score = 24 4. Montreal Cognitive Assessment (MOCA) score < 26 5. Patients able to understand and sign informed consent 6. Informed consent signature.
Exclusion: Any contraindication to treatment or intolerance to choline alfoscerate 2. Diagnosis of Major Depressive Episode or Dysthymia 3. Diagnosis of Schizophrenia or other psychotic disorders, Bipolar Disorder or Dementia 4. Alcohol / drug / substance abuse or dependence 5. Severe organic disease (eg major surgery, metastatic cancer, stroke, severe neurological disorder, myocardial infarction, chronic heart failure) 6. Treatment with antidepressants or psychotherapy within 2 weeks prior to recruitment 7. Any condition which, in the opinion of the investigator, might put the patient at risk by participation in this study 8. Patients involved in other clinical trials.