The Surf trial
Key facts
- Where
- Rotterdam, HollandiaSee the site
- Phase
- 2/3. fázis
Where in Hollandia
- Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)Rotterdam, HollandiaToborzás még nem indult
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
- Trial code
- EU 2025-523898-42-00
- Record updated
- 2026. április 28.
- Original description
To determine the optimal dose and timing of intravenous ICG to achieve sufficient tumor-to background contrast in solid tumors and to evaluate whether ICG fluorescence imaging can accurately identify tumor margins during surgery.Read full original descriptionShow less
The SURF trial: Optimizing Surgical excision Using Real-time Fluorescence imaging with indocyanine green
To determine the optimal dose and timing of intravenous ICG to achieve sufficient tumor-to background contrast in solid tumors and to evaluate whether ICG fluorescence imaging can accurately identify tumor margins during surgery.
Inclusion: Age ≥18 years; Histologically confirmed solid malignancy (e.g., head and neck, gastrointestinal, hepatobiliary, breast, genitourinary, sarcoma); Candidate for surgical resection with curative intent; Ability to provide written informed consent; Adequate organ function to undergo surgery and ICG administration.
Exclusion: Known allergy to Indocyanine Green (ICG), iodine, or shellfish; Hyperthyroidism or other active thyroid disease; Any condition deemed by the investigator to place the patient at undue risk or interfere with study procedures; Significant renal impairment (eGFR <50 mL/min/1.73 m²); Pregnant or breastfeeding.