Molecular and Morphologic Characterization of Circulating Endothelial Cells

Korábbi kezelés

• Previous history of coronary artery disease or MI

Más betegség

• 1\. Has a significant medical condition that in the investigator's opinion may interfere with the patient's optimal participation in the study.
• Diabetes
• Peripheral arterial disease
• Hypertension (\>140/90 or on blood pressure medication)
• Sickle cell disease
• Acute or Chronic kidney disease
• Acute or Chronic vascular conditions, not otherwise specified
• Active or history of inflammation of connective tissue and vascular structures (i.e. vasculitis, rheumatoid arthritis)

Életkor

• Age greater than 35

Egyéb

• General Exclusion Criteria:
• Exclusion for Healthy Controls:

• Age 18 - 80 years old.
• Must be reliable, cooperative and willing to comply with all protocol-specified procedures if consented.
• Able to understand and grant informed consent
• Subjects must meet one of the following (a-c):
  • Healthy control subjects not meeting any exclusion criteria for controls below
  • Patients scheduled for an open vascular procedure of an arterial structure
  • Patients with acute MI defined as:
  • Clinical history and symptoms consistent with acute MI AND ii Elevated cardiac markers (CKMB, Troponin I or T) consistent with MI (abnormals are according to enrolling institution's lab standards) AND iii. Able to complete study enrollment (consent \& blood draw) within 48 hours of presentation to the study site.