Early Identification of Patients Presenting a First Psychotic Episode, Non Answering to First Line Support Strategies

Korábbi kezelés

• Female patients of childbearing period without effective contraception (oral, intramuscular hormonal, intrauterine device, or surgical);
• Participating in another clinical trial or being in an exclusion period of the previous protocol;

Más betegség

• Presenting a serious somatic or neurological disease, especially Parkinson's disease, epilepsy, debilitating tardive dyskinesia, cardiovascular disease, severe liver or kidney;
• Featuring against-indication for an MRI; including: metallic foreign body eye or intracranial, pacemaker, heart valve, surgical clips, claustrophobia, large tattoo in the upper part of the body, not compatible with 3T MRI
• Having a history of alcohol or drug abuse in the past year;

Egyéb

• Patients pregnant or nursing;
• Patients likely to exhibit aggressive behavior self according to the judgment of the investigators.

• men and women aged 18-35 years
• member or beneficiary of a social security scheme,
• for women, appropriate contraception will be mandatory, as well as a negative pregnancy test,
• patients with a diagnosis of schizophrenia, schizoaffective disorder or schizophreniform disorder according to the DMS V
• having never received anti-psychotic treatment,
• followed in the hospital or outpatient,
• having given their written informed consent,
• that the physical examination revealed no significant clinical abnormalities