Gut Microbiome in AP Naive

Korábbi kezelés

• Previous antipsychotic treatment (greater than two weeks within the preceding 3 months)
• Use of other medications where the dose has changed within the past 6 weeks which are deemed by the PI to be clinically significant
• Eating disorder - active or previous
• Major medical or surgical event within the preceding 3 months
• Organ transplant
• Moderate to severe alcohol use , use of street drugs, and/or cannabis use (as deemed by PI)
• Immunosuppressants and/or anti-inflammatory medications

Más betegség

• Presence of DSM-5 diagnosis which is not schizophrenia, schizoaffective disorder, or other specified schizophrenia spectrum and other psychotic disorder
• Irritable bowel disease, Crohn's disease, and/or diverticulitis/diverticulosis
• Type I diabetes, kidney/liver disease, and/or cancer
• Any other medical conditions or lifestyle habits deemed by the PI to impact the integrity of the sample/microbiota

Laborértékek

• Use of any other medications for treatment of lipids, glucose, or weight as deemed to be clinically significant by the PI

Egyéb

• Pregnancy
• Acute suicidal risk
• Antibiotic/probiotic use within past 4 weeks

• Ages 12-35
• Antipsychotic naïve or antipsychotic treatment for equal to or less than 2 weeks within the past 3 months; the minimum AP dose will be left to the discretion of the PI
• DSM-5 diagnosis (using SCID-IV-TR with supplemental questions from SCID-5 or SCID-5) of schizophrenia, schizoaffective disorder, schizophreniform disorder, delusional disorder, and brief psychotic disorder, psychotic disorder NOS. and/or antipsychotic treatment for schizophrenia, schizoaffective disorder, or other specified schizophrenia spectrum and other psychotic disorder.