Radiofrequency in Differentiated Thyroid Cancer Metastatic Lymph Node: Prospective Study of Safety and Efficacy

Korábbi kezelés

• Patient who can't follow the instructions of RF therapy or who can't be followed during 2 years in order to meet the objectives of the study
• Beta hormone chorionic gonadotrope (HCG) positive test (pregnancy) before RF therapy

Más betegség

• Hypersensitivity to local anesthetic
• Poor general condition (performance status Eastern Cooperative Oncology Group (ECOG) \> 1)

Laborértékek

• Congenital or acquired hemostasis abnormality, anticoagulant therapy or double platelet antiaggregatory (aspirin and clopidogrel)

Egyéb

• Location of LN metastasis with significant risk of local complication (nervous, vascular) according baseline ultrasound assessment
• Patient carrier of a pacemaker or a defibrillator
• Survival estimated less than 12 months
• Non affiliation to a social security
• Pregnant or breast feeding women at the time of RF
• Baseline cervical ultrasound, by expert operator trained to RF, not fulfilling feasibility criteria for RF realisation because of the location of LN metastasis or the way to reach it
• Controlateral recurrent palsy on nasofibroscopy

• Patients over age of 18 years
• with differentiated thyroid cancer (papillary, follicular) histologically confirmed, and absence of anaplastic component
• Previous treatment by total thyroidectomy and cervical lymph node dissection.
• Previous treatment by at least 1 therapeutic radioactive iodine (minimum activity 740MBq)
• Persistence on cervical ultrasound of at least 1 cervical metastatic lymph node, visible at ultrasound, small diameter between ≥10 mm and ≤30mm, volume maximum 20ml, spotted on a picture, and confirmed by cyto-punction
• Signed informed consent