Contrast Enhanced Ultrasound in Human Crohn's Disease-Lumason

Korábbi kezelés

• Prior allergic-like reaction or other severe adverse event to Lumason or any of the active ingredients in Lumason (SPECIFIC CONTRAINDICATION from Package Insert).

Más betegség

• Obesity/body habitus preventing visualization of small bowel affected by Crohn's disease by ultrasound (Body mass index ≥30 kg/m2

Laborértékek

• Known unstable cardiopulmonary conditions (including any history of acute myocardial infarction/acute coronary artery syndrome, arrhythmia, and congestive heart failure), ongoing acute or chronic kidney disease (eGFR <30 ml/min), moderate/severe chronic lung disease, and end-stage liver disease.

Életkor

• Patients under the age of 10 or over the age of 18.

Egyéb

• Pregnancy or breast feeding. Urine pregnancy testing will be performed on all female study participants of reproductive potential.
• Subject inability/unwillingness to consent or child assent, including severe developmental delay/mental retardation.

• histologic evidence of small bowel Crohn's disease, or clinical evidence of disease (including radiologic confirmation [either CT or MRI] and receiving medical therapy for Crohn's disease).
• Between ages 10 and 18 years.
• Undergoing clinically-indicated CTE or MRE with evidence of active disease based on pediatric gastroenterologist clinical assessment