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Taking people in Németország2. fázis

International Study for Treatment of High Risk Childhood Relapsed ALL 2010

Key facts

Where
Aachen, Augsburg, Berlin, Bielefeld, Bonn, Bremen, Brunswick, Cologne, Cottbus, Datteln, Dortmund, Dresden, Duesseldorf, Erfurt, Erlangen, Essen, Frankfurt Am Main, Freiburg im Breisgau, Giessen, Goettingen, Greifswald, Halle Saale, Hamburg, Herdecke, Homburg, Jena, Karlsruhe, Kassel, Kiel, Koblenz, Leipzig, Magdeburg, Mainz, Muenster, Munich, Oldenburg, Regensburg, Rostock, Sankt Augustin, Schwerin, Stuttgart, Tuebingen, Ulm és Wuerzburg, NémetországSee the 47 sites
Phase
2. fázis

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • How old is the patient who may join a trial?
  • What type of cancer has the patient been diagnosed with?
  • Is this cancer newly diagnosed, or has it come back or not responded to treatment?
  • Is the patient pregnant or breastfeeding?

Forrás: NCT03590171: ki vehet részt

Where in Németország

  • Universitaetsklinikum Aachen AöRAachen, NémetországTaking people
  • Universitaetsklinikum AugsburgAugsburg, NémetországTaking people
  • Charite Universitaetsmedizin Berlin KöRBerlin, NémetországTaking people
  • HELIOS Kliniken GmbHBerlin, NémetországTaking people
  • Evangelisches Klinikum Bethel gGmbHBielefeld, NémetországTaking people
  • Universitaetsklinikum Bonn AöRBonn, NémetországTaking people
  • Gesundheit Nord gGmbH Klinikverbund BremenBremen, NémetországTaking people
  • Staedtisches Klinikum Braunschweig gGmbHBrunswick, NémetországTaking people
  • Kliniken der Stadt Koeln gGmbHCologne, NémetországTaking people
  • University Hospital Cologne AöRCologne, NémetországTaking people
  • Carl-Thiem-Klinikum Cottbus gGmbHCottbus, NémetországTaking people
  • Vestische Kinder- und Jugendklinik DattelnDatteln, NémetországTaking people
  • Klinikum Dortmund gGmbHDortmund, NémetországTaking people
  • Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöRDresden, NémetországTaking people
  • Universitaetsklinikum Duesseldorf AöRDuesseldorf, NémetországTaking people
  • HELIOS Klinikum Erfurt GmbHErfurt, NémetországTaking people
  • Universitaetsklinikum Erlangen AöRErlangen, NémetországTaking people
  • Universitaetsklinikum Essen (AoR)Essen, NémetországTaking people
  • Universitaetsklinikum Frankfurt AöRFrankfurt Am Main, NémetországTaking people
  • Medical Center- University of FreiburgFreiburg im Breisgau, NémetországTaking people
  • Justus-Liebig-Universitaet GiessenGiessen, NémetországTaking people
  • Universitaetsmedizin GoettingenGoettingen, NémetországTaking people
  • Universitaetsmedizin Greifswald KöRGreifswald, NémetországTaking people
  • Universitaetsklinikum Halle (Saale) AöRHalle Saale, NémetországTaking people
  • University Medical Center Hamburg-EppendorfHamburg, NémetországTaking people
  • Gemeinschaftskrankenhaus Herdecke gGmbHHerdecke, NémetországTaking people
  • Universitaetsklinikum des Saarlandes AöRHomburg, NémetországTaking people
  • Universitaetsklinikum Jena KöRJena, NémetországTaking people
  • Staedtisches Klinikum Karlsruhe gGmbHKarlsruhe, NémetországTaking people
  • Klinikum Kassel GmbHKassel, NémetországTaking people
  • Universitaetsklinikum Schleswig-Holstein AöRKiel, NémetországTaking people
  • Gemeinschaftsklinikum Mittelrhein gGmbHKoblenz, NémetországTaking people
  • Universitaetsklinikum Leipzig AorLeipzig, NémetországTaking people
  • Universitaetsklinikum Magdeburg AöRMagdeburg, NémetországTaking people
  • Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöRMainz, NémetországTaking people
  • Universitaetsklinikum Muenster AöRMuenster, NémetországTaking people
  • Klinikum der Universitaet Muenchen AöRMunich, NémetországTaking people
  • Muenchen Klinik gGmbHMunich, NémetországTaking people
  • Klinikum Oldenburg AorOldenburg, NémetországTaking people
  • Universitaetsklinikum Regensburg AöRRegensburg, NémetországTaking people
  • Universitaet RostockRostock, NémetországTaking people
  • Asklepios-Klinik, Sankt Augustin GmbHSankt Augustin, NémetországTaking people
  • HELIOS Kliniken Schwerin GmbHSchwerin, NémetországTaking people
  • Klinikum Der Landeshauptstadt Stuttgart gKAöRStuttgart, NémetországTaking people
  • Universitaetsklinikum Tuebingen AöRTuebingen, NémetországTaking people
  • Universitaetsklinikum Ulm AoRUlm, NémetországTaking people
  • Universitaetsklinikum Wuerzburg AöRWuerzburg, NémetországTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Charite University, Berlin, Germany
Trial code
NCT03590171EU 2024-513070-21-00
Record updated
2026. március 17.
Original description
The main goal of this study is to improve the outcome of children and adolescents with acute lymphoblastic leukemia with high risk first relapse by optimization of treatment strategies within a large international trial and the integration of new agents.Read full original descriptionShow less

International Study for Treatment of High Risk Childhood Relapsed ALL 2010 A Randomized Phase II Study Conducted by the Resistant Disease Committee of the International Berlin, Frankfurt, Münster (BFM) Study Group

The main goal of this study is to improve the outcome of children and adolescents with acute lymphoblastic leukemia with high risk first relapse by optimization of treatment strategies within a large international trial and the integration of new agents.

Inclusion: Morphologically confirmed diagnosis of 1st relapsed precursor B-cell or T-cell ALL; Children less than 18 years of age at date of inclusion into the study; Meeting HR criteria any BM relapse, early/very early isolated BM relapse, very early isolated/combined extramedullary relapse); Patient enrolled in a participating centre; Written informed consent; Start of treatment falling into the study period; No participation in other clinical trials 30 day prior to study enrolment that interfere with this protocol, except trials for primary ALL.

Exclusion: Sexually active adolescents not willing to use highly effective contraceptive method (pearl index <1) until 12 months after end of anti-leukemic therapy; Relapse post allogeneic stem-cell transplantation; Severe concomitant disease that does not allow treatment according to the protocol at the investigator's discretion (e.g. malformation syndromes, cardiac malformations, metabolic disorders); Breakpoint cluster region-Abelson (BCR-ABL)/ t(9;22) positive ALL; Pregnancy or positive pregnancy test (urine sample positive for β-humane choriongonadotropin (HCG) > 10 U/l); Breast feeding; Neuropathy > II°; The whole protocol or essential parts are declined either by patient himself/herself or the respective legal guardian; Objection to the study participation by a minor patient, able to object; Any patient being dependent on the investigator; No consent is given for saving and propagation of pseudonymized medical data for study reasons; Subjects unwilling or unable to comply with the study procedures; Subjects who are legally detained in an official institute.

ClinicalTrials.gov NCT03590171 · EU CTIS 2024-513070-21-00