Felfüggesztve2/3. fázis

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Megadott ok: End of Initial Phase of Multi-phase protocol

Key facts

Where: ‘Aiea, Aberdeen, Albuquerque, Allentown, Altamonte Springs, Altoona, Anchorage, Ann Arbor, Appleton, Arroyo Grande, Ashland, Atlanta, Aventura, Ballwin, Bangor, Bath, Beaver, Beavercreek, Bellevue, Bellingham, Bemidji, Bend, Berlin Corners, Bethlehem, Biddeford, Bismarck, Bloomington, Boardman, Boise, Bolivar, Boston, Brainerd, Brewer, Brick, Bridgeport, Brighton, Bryan, Burbank, Burien, Burlington, Burnsville, Butler, Camp Hill, Canandaigua, Canton, Cape Girardeau, Carbondale, Carlisle, Carmel, Caro, Carterville, Carthage, Centerville, Centralia, Chadds Ford, Charleston, Charlotte, Charlottesville, Chelsea, Chicago, Cincinnati, City of Saint Peters, Clackamas, Cleveland, Clive, Clovis, Collierville, Colorado Springs, Columbus, Coon Rapids, Coos Bay, Creston, Creve Coeur, Dallas, Dansville, Danville, Dayton, Decatur, Deer River, Denver, Des Moines, Detroit, Detroit Lakes, Dixon, Duluth, East Greenwich, East Stroudsburg, Easton, Eau Claire, Edina, Edmonds, Effingham, Erie, Eureka, Everett, Fargo, Farmington, Farrell, Fergus Falls, Findlay, Flint, Fond du Lac, Fort Lauderdale, Fort Myers, Fort Smith, Fort Worth, Fosston, Franklin, Fridley, Fruitland, Gainesville, Galesburg, Garden City, Germantown, Glens Falls, Grafton, Grand Island, Great Bend, Green Bay, Greensburg, Greenville, Grenada, Grosse Pointe Woods, Harrisburg, Hayward, Henderson, Hershey, Hibbing, Hines, Honolulu, Hot Springs, Huntersville, Independence, Indiana, Indianapolis, Issaquah, Jamestown, Jefferson City, Jefferson Hills, Johnson Creek, Johnstown, Jonesboro, Joplin, Kearney, Kenner, Kenosha, Kernersville, Kettering, Kewanee, Kissimmee, Lacey, Lake Forest, Lake Success, Lakewood, Lansing, Las Vegas, Lebanon, Lewes, Lewisburg, Lexington, Lihue, Littleton, Livonia, Long Branch, Longmont, Longview, Los Angeles, Louisville, Lowell, Macomb, Madison, Manahawkin, Mansfield, Maple Grove, Maplewood, Marinette, Marlette, Marshfield, Matthews, Mayfield Heights, Maywood, McKeesport, Memphis, Meridian, Miami Beach, Middletown, Millville, Milwaukee, Minneapolis, Minocqua, Missoula, Monroeville, Monticello, Moon Township, Mooresville, Morgantown, Mount Airy, Mount Pleasant, Mount Vernon, N. Huntingdon, Nampa, Nashville, Natrona Heights, Neptune City, New Albany, New Brunswick, New Castle, New Orleans, New Richmond, New York, Newark, Newberg, Newport, North Wilkesboro, Novi, O'Fallon, Oklahoma City, Omaha, Orlando, Oshkosh, Ottawa, Oxford, Palo Alto, Park Rapids, Parker, Parkersburg, Pekin, Peoria, Peru, Philadelphia, Phoenix, Pittsburgh, Pontiac, Portland, Pottstown, Princeton, Providence, Pueblo, Racine, Red Bank, Rehoboth Beach, Reno, Renton, Rice Lake, Richardson, Richmond, Rio Rancho, Robbinsdale, Rochester, Rolla, Sacramento, Saginaw, Saint Johnsbury, Saint Joseph, Saint Louis Park, Saint Paul, Sainte Genevieve, Salisbury, Salt Lake City, San Luis Obispo, Sandstone, Sandusky, Sanford, Santa Maria, Savannah, Scarborough, Seaford, Seattle, Sedro-Woolley, Seneca, Shakopee, Sheboygan, Silverdale, Sioux Falls, South Hill, South Portland, Southfield, Southhaven, Spooner, Springfield, St Louis, St. Helena, Statesville, Stevens Point, Stillwater, Strongsville, Sturgeon Bay, Sullivan, Summit, Superior, Sylvania, Syracuse, Tacoma, Tawas City, The Bronx, Thomasville, Toledo, Toms River, Troy, Twin Falls, Two Rivers, Uniontown, Vancouver, Virginia, Waconia, Walla Walla, Warren, Warrensville Heights, Washington, Washington D.C., Wauwatosa, West Allis, West Branch, West Chester, West Des Moines, West Mifflin, West Reading, Weston, Wexford, Whittier, Willmar, Winston-Salem, Woodbury, Woodland, Wooster, Yakima, York, Youngstown és Ypsilanti, Egyesült ÁllamokSee the 488 sites
Phase: 2/3. fázis

Where in Egyesült Államok

Hawaii Cancer Care - Westridge‘Aiea, Egyesült ÁllamokNo longer taking part
Pali Momi Medical Center‘Aiea, Egyesült ÁllamokNo longer taking part
Queen's Cancer Center - Pearlridge‘Aiea, Egyesült ÁllamokNo longer taking part
The Cancer Center of Hawaii-Pali Momi‘Aiea, Egyesült ÁllamokNo longer taking part
Providence Regional Cancer System-AberdeenAberdeen, Egyesült ÁllamokNo longer taking part
Lovelace Medical Center-Saint Joseph SquareAlbuquerque, Egyesült ÁllamokNo longer taking part
New Mexico Oncology Hematology ConsultantsAlbuquerque, Egyesült ÁllamokNo longer taking part
Presbyterian Kaseman HospitalAlbuquerque, Egyesült ÁllamokNo longer taking part
University of New Mexico Cancer CenterAlbuquerque, Egyesült ÁllamokNo longer taking part
Lehigh Valley Hospital-Cedar CrestAllentown, Egyesült ÁllamokNo longer taking part
Saint Luke's Cancer Center - AllentownAllentown, Egyesült ÁllamokNo longer taking part
AdventHealth AltamonteAltamonte Springs, Egyesült ÁllamokNo longer taking part
UPMC AltoonaAltoona, Egyesült ÁllamokNo longer taking part
Alaska Breast Care and Surgery LLCAnchorage, Egyesült ÁllamokNo longer taking part
Alaska Oncology and Hematology LLCAnchorage, Egyesült ÁllamokNo longer taking part
Alaska Women's Cancer CareAnchorage, Egyesült ÁllamokNo longer taking part
Anchorage Associates in Radiation MedicineAnchorage, Egyesült ÁllamokNo longer taking part
Anchorage Oncology CentreAnchorage, Egyesült ÁllamokNo longer taking part
Katmai Oncology GroupAnchorage, Egyesült ÁllamokNo longer taking part
Providence Alaska Medical CenterAnchorage, Egyesült ÁllamokNo longer taking part
Trinity Health Saint Joseph Mercy Hospital Ann ArborAnn Arbor, Egyesült ÁllamokNo longer taking part
ThedaCare Regional Cancer CenterAppleton, Egyesült ÁllamokNo longer taking part
PCR OncologyArroyo Grande, Egyesült ÁllamokNo longer taking part
Duluth Clinic AshlandAshland, Egyesült ÁllamokNo longer taking part
Northwest Wisconsin Cancer CenterAshland, Egyesült ÁllamokNo longer taking part
Emory Proton Therapy CenterAtlanta, Egyesült ÁllamokNo longer taking part
Emory Saint Joseph's HospitalAtlanta, Egyesült ÁllamokNo longer taking part
Emory University Hospital MidtownAtlanta, Egyesült ÁllamokNo longer taking part
Emory University Hospital/Winship Cancer InstituteAtlanta, Egyesült ÁllamokNo longer taking part
Mount Sinai Comprehensive Cancer Center at AventuraAventura, Egyesült ÁllamokNo longer taking part
Mercy Oncology and Hematology - Clayton-ClarksonBallwin, Egyesült ÁllamokNo longer taking part
Eastern Maine Medical CenterBangor, Egyesült ÁllamokNo longer taking part
MaineHealth Coastal Cancer Treatment CenterBath, Egyesült ÁllamokNo longer taking part
UPMC-Heritage Valley Health System BeaverBeaver, Egyesült ÁllamokNo longer taking part
Indu and Raj Soin Medical CenterBeavercreek, Egyesült ÁllamokNo longer taking part
Nebraska Medicine-BellevueBellevue, Egyesült ÁllamokNo longer taking part
Overlake Medical CenterBellevue, Egyesült ÁllamokNo longer taking part
PeaceHealth Saint Joseph Medical CenterBellingham, Egyesült ÁllamokNo longer taking part
Sanford Joe Lueken Cancer CenterBemidji, Egyesült ÁllamokNo longer taking part
Saint Charles Health SystemBend, Egyesült ÁllamokNo longer taking part
Central Vermont Medical Center/National Life Cancer TreatmentBerlin Corners, Egyesült ÁllamokNo longer taking part
Lehigh Valley Hospital - MuhlenbergBethlehem, Egyesült ÁllamokNo longer taking part
Saint Luke's University Hospital-Bethlehem CampusBethlehem, Egyesült ÁllamokNo longer taking part
MaineHealth Maine Medical Center - BiddefordBiddeford, Egyesült ÁllamokNo longer taking part
Sanford Bismarck Medical CenterBismarck, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-BloomingtonBloomington, Egyesült ÁllamokNo longer taking part
Saint Elizabeth Boardman HospitalBoardman, Egyesült ÁllamokNo longer taking part
Saint Luke's Cancer Institute - BoiseBoise, Egyesült ÁllamokNo longer taking part
Central Care Cancer Center - BolivarBolivar, Egyesült ÁllamokNo longer taking part
Boston Medical CenterBoston, Egyesült ÁllamokNo longer taking part
Tufts Medical CenterBoston, Egyesült ÁllamokNo longer taking part
Essentia Health Saint Joseph's Medical CenterBrainerd, Egyesült ÁllamokNo longer taking part
Lafayette Family Cancer Center-EMMCBrewer, Egyesült ÁllamokNo longer taking part
Ocean University Medical CenterBrick, Egyesült ÁllamokNo longer taking part
United Hospital CenterBridgeport, Egyesült ÁllamokNo longer taking part
Trinity Health IHA Medical Group Hematology Oncology - BrightonBrighton, Egyesült ÁllamokNo longer taking part
Trinity Health Medical Center - BrightonBrighton, Egyesült ÁllamokNo longer taking part
Saint Joseph Regional Cancer CenterBryan, Egyesült ÁllamokNo longer taking part
Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, Egyesült ÁllamokNo longer taking part
Saint Anne HospitalBurien, Egyesült ÁllamokNo longer taking part
Aurora Cancer Care-Southern Lakes VLCCBurlington, Egyesült ÁllamokNo longer taking part
University of Vermont and State Agricultural CollegeBurlington, Egyesült ÁllamokNo longer taking part
University of Vermont Medical CenterBurlington, Egyesült ÁllamokNo longer taking part
Fairview Ridges HospitalBurnsville, Egyesült ÁllamokNo longer taking part
Minnesota Oncology - BurnsvilleBurnsville, Egyesült ÁllamokNo longer taking part
UPMC Hillman Cancer Center at Butler Health SystemButler, Egyesült ÁllamokNo longer taking part
UPMC Camp HillCamp Hill, Egyesült ÁllamokNo longer taking part
Sands Cancer CenterCanandaigua, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-CantonCanton, Egyesült ÁllamokNo longer taking part
Trinity Health IHA Medical Group Hematology Oncology - CantonCanton, Egyesült ÁllamokNo longer taking part
Trinity Health Medical Center - CantonCanton, Egyesült ÁllamokNo longer taking part
Mercy Cancer Center - Cape GirardeauCape Girardeau, Egyesült ÁllamokNo longer taking part
Saint Francis Medical CenterCape Girardeau, Egyesült ÁllamokNo longer taking part
Memorial Hospital of CarbondaleCarbondale, Egyesült ÁllamokNo longer taking part
Carlisle Regional Cancer CenterCarlisle, Egyesült ÁllamokNo longer taking part
IU Health North HospitalCarmel, Egyesült ÁllamokNo longer taking part
Caro Cancer CenterCaro, Egyesült ÁllamokNo longer taking part
SIH Cancer InstituteCarterville, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-CarthageCarthage, Egyesült ÁllamokNo longer taking part
Dayton Physicians LLC-Miami Valley SouthCenterville, Egyesült ÁllamokNo longer taking part
Miami Valley Hospital SouthCenterville, Egyesült ÁllamokNo longer taking part
Centralia Oncology ClinicCentralia, Egyesült ÁllamokNo longer taking part
Providence Regional Cancer System-CentraliaCentralia, Egyesült ÁllamokNo longer taking part
Christiana Care Health System-Concord Health CenterChadds Ford, Egyesült ÁllamokNo longer taking part
Medical University of South CarolinaCharleston, Egyesült ÁllamokNo longer taking part
Vandalia Health/CAMC Institute for Academic MedicineCharleston, Egyesült ÁllamokNo longer taking part
Novant Health Presbyterian Medical CenterCharlotte, Egyesült ÁllamokNo longer taking part
University of Virginia Cancer CenterCharlottesville, Egyesült ÁllamokNo longer taking part
Chelsea HospitalChelsea, Egyesült ÁllamokNo longer taking part
Trinity Health IHA Medical Group Hematology Oncology - Chelsea HospitalChelsea, Egyesült ÁllamokNo longer taking part
Northwestern UniversityChicago, Egyesült ÁllamokNo longer taking part
University of IllinoisChicago, Egyesült ÁllamokNo longer taking part
Bethesda North HospitalCincinnati, Egyesült ÁllamokNo longer taking part
Good Samaritan Hospital - CincinnatiCincinnati, Egyesült ÁllamokNo longer taking part
Oncology Hematology Care Inc-KenwoodCincinnati, Egyesült ÁllamokNo longer taking part
University of Cincinnati Cancer Center-UC Medical CenterCincinnati, Egyesült ÁllamokNo longer taking part
Siteman Cancer Center at Saint Peters HospitalCity of Saint Peters, Egyesült ÁllamokNo longer taking part
Clackamas Radiation Oncology CenterClackamas, Egyesült ÁllamokNo longer taking part
Providence Cancer Institute Clackamas ClinicClackamas, Egyesült ÁllamokNo longer taking part
Cleveland Clinic Cancer Center/Fairview HospitalCleveland, Egyesült ÁllamokNo longer taking part
Cleveland Clinic FoundationCleveland, Egyesült ÁllamokNo longer taking part
MetroHealth Medical CenterCleveland, Egyesült ÁllamokNo longer taking part
Mercy Cancer Center-West LakesClive, Egyesült ÁllamokNo longer taking part
UI Health Care Mission Cancer and Blood - West Des Moines ClinicClive, Egyesült ÁllamokNo longer taking part
Community Cancer InstituteClovis, Egyesült ÁllamokNo longer taking part
University Oncology AssociatesClovis, Egyesült ÁllamokNo longer taking part
Baptist Memorial Hospital and Cancer Center-ColliervilleCollierville, Egyesült ÁllamokNo longer taking part
Penrose-Saint Francis HealthcareColorado Springs, Egyesült ÁllamokNo longer taking part
Rocky Mountain Cancer Centers-PenroseColorado Springs, Egyesült ÁllamokNo longer taking part
Saint Francis Cancer CenterColorado Springs, Egyesült ÁllamokNo longer taking part
Baptist Memorial Hospital and Cancer Center-Golden TriangleColumbus, Egyesült ÁllamokNo longer taking part
Ohio State University Comprehensive Cancer CenterColumbus, Egyesült ÁllamokNo longer taking part
Mercy HospitalCoon Rapids, Egyesült ÁllamokNo longer taking part
Bay Area HospitalCoos Bay, Egyesült ÁllamokNo longer taking part
Greater Regional Medical CenterCreston, Egyesült ÁllamokNo longer taking part
Siteman Cancer Center at West County HospitalCreve Coeur, Egyesült ÁllamokNo longer taking part
Parkland Memorial HospitalDallas, Egyesült ÁllamokNo longer taking part
UT Southwestern/Simmons Cancer Center-DallasDallas, Egyesült ÁllamokNo longer taking part
Noyes Memorial Hospital/Myers Cancer CenterDansville, Egyesült ÁllamokNo longer taking part
Geisinger Medical CenterDanville, Egyesült ÁllamokNo longer taking part
Dayton Physician LLC - EnglewoodDayton, Egyesült ÁllamokNo longer taking part
Miami Valley HospitalDayton, Egyesült ÁllamokNo longer taking part
Miami Valley Hospital NorthDayton, Egyesült ÁllamokNo longer taking part
Cancer Care Specialists of Illinois - DecaturDecatur, Egyesült ÁllamokNo longer taking part
Decatur Memorial HospitalDecatur, Egyesült ÁllamokNo longer taking part
Essentia Health - Deer River ClinicDeer River, Egyesült ÁllamokNo longer taking part
AdventHealth PorterDenver, Egyesült ÁllamokNo longer taking part
Mercy Medical Center - Des MoinesDes Moines, Egyesült ÁllamokNo longer taking part
UI Health Care Mission Cancer and Blood - Laurel ClinicDes Moines, Egyesült ÁllamokNo longer taking part
Henry Ford Health Saint John HospitalDetroit, Egyesült ÁllamokNo longer taking part
Essentia Health Saint Mary's - Detroit Lakes ClinicDetroit Lakes, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-DixonDixon, Egyesült ÁllamokNo longer taking part
Essentia Health Cancer CenterDuluth, Egyesült ÁllamokNo longer taking part
Essentia Health Saint Mary's Medical CenterDuluth, Egyesült ÁllamokNo longer taking part
Miller-Dwan HospitalDuluth, Egyesült ÁllamokNo longer taking part
Rhode Island Hospital at East GreenwichEast Greenwich, Egyesült ÁllamokNo longer taking part
Pocono Medical CenterEast Stroudsburg, Egyesült ÁllamokNo longer taking part
Saint Luke's Hospital-Anderson CampusEaston, Egyesült ÁllamokNo longer taking part
HSHS Sacred Heart HospitalEau Claire, Egyesült ÁllamokNo longer taking part
Marshfield Medical Center-EC Cancer CenterEau Claire, Egyesült ÁllamokNo longer taking part
Fairview Southdale HospitalEdina, Egyesült ÁllamokNo longer taking part
Minnesota Oncology - EdinaEdina, Egyesült ÁllamokNo longer taking part
Swedish Cancer Institute-EdmondsEdmonds, Egyesült ÁllamokNo longer taking part
Crossroads Cancer CenterEffingham, Egyesült ÁllamokNo longer taking part
UPMC Hillman Cancer Center ErieErie, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-EurekaEureka, Egyesült ÁllamokNo longer taking part
Providence Regional Cancer PartnershipEverett, Egyesült ÁllamokNo longer taking part
Essentia Health Cancer Center-South University ClinicFargo, Egyesült ÁllamokNo longer taking part
Sanford Broadway Medical CenterFargo, Egyesült ÁllamokNo longer taking part
Sanford Roger Maris Cancer CenterFargo, Egyesült ÁllamokNo longer taking part
Parkland Health Center - FarmingtonFarmington, Egyesült ÁllamokNo longer taking part
UPMC Cancer Center at UPMC HorizonFarrell, Egyesült ÁllamokNo longer taking part
Lake Region Healthcare Corporation-Cancer CareFergus Falls, Egyesült ÁllamokNo longer taking part
Armes Family Cancer CenterFindlay, Egyesült ÁllamokNo longer taking part
Blanchard Valley HospitalFindlay, Egyesült ÁllamokNo longer taking part
Orion Cancer CareFindlay, Egyesült ÁllamokNo longer taking part
Genesys Hurley Cancer InstituteFlint, Egyesült ÁllamokNo longer taking part
Hurley Medical CenterFlint, Egyesült ÁllamokNo longer taking part
Aurora Health Center-Fond du LacFond du Lac, Egyesült ÁllamokNo longer taking part
Holy Cross HospitalFort Lauderdale, Egyesült ÁllamokNo longer taking part
Regional Cancer Center-Lee Memorial Health SystemFort Myers, Egyesült ÁllamokNo longer taking part
Mercy Hospital Fort SmithFort Smith, Egyesült ÁllamokNo longer taking part
UT Southwestern/Simmons Cancer Center-Fort WorthFort Worth, Egyesült ÁllamokNo longer taking part
Essentia Health - FosstonFosston, Egyesült ÁllamokNo longer taking part
Atrium Medical Center-Middletown Regional HospitalFranklin, Egyesült ÁllamokNo longer taking part
Dayton Physicians LLC-AtriumFranklin, Egyesült ÁllamokNo longer taking part
Unity HospitalFridley, Egyesült ÁllamokNo longer taking part
Saint Luke's Cancer Institute - FruitlandFruitland, Egyesült ÁllamokNo longer taking part
UF Health Cancer Institute - GainesvilleGainesville, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-GalesburgGalesburg, Egyesült ÁllamokNo longer taking part
Western Illinois Cancer Treatment CenterGalesburg, Egyesült ÁllamokNo longer taking part
Central Care Cancer Center - Garden CityGarden City, Egyesült ÁllamokNo longer taking part
Aurora Health Care Germantown Health CenterGermantown, Egyesült ÁllamokNo longer taking part
Glens Falls HospitalGlens Falls, Egyesült ÁllamokNo longer taking part
Aurora Cancer Care-GraftonGrafton, Egyesült ÁllamokNo longer taking part
Nebraska Cancer Specialists/Oncology Hematology West PCGrand Island, Egyesült ÁllamokNo longer taking part
Central Care Cancer Center - Great BendGreat Bend, Egyesült ÁllamokNo longer taking part
Aurora BayCare Medical CenterGreen Bay, Egyesült ÁllamokNo longer taking part
Bellin Memorial HospitalGreen Bay, Egyesült ÁllamokNo longer taking part
Saint Vincent Hospital Cancer Center at Saint Mary'sGreen Bay, Egyesült ÁllamokNo longer taking part
Saint Vincent Hospital Cancer Center Green BayGreen Bay, Egyesült ÁllamokNo longer taking part
UPMC Cancer Centers - Arnold Palmer PavilionGreensburg, Egyesült ÁllamokNo longer taking part
Dayton Physicians LLC-WayneGreenville, Egyesült ÁllamokNo longer taking part
Saint Francis Cancer CenterGreenville, Egyesült ÁllamokNo longer taking part
Saint Francis HospitalGreenville, Egyesült ÁllamokNo longer taking part
Wayne HospitalGreenville, Egyesült ÁllamokNo longer taking part
Baptist Cancer Center-GrenadaGrenada, Egyesült ÁllamokNo longer taking part
Henry Ford Saint John Hospital - Van ElslanderGrosse Pointe Woods, Egyesült ÁllamokNo longer taking part
UPMC Pinnacle Cancer Center/Community Osteopathic CampusHarrisburg, Egyesült ÁllamokNo longer taking part
Essentia Health-Hayward ClinicHayward, Egyesült ÁllamokNo longer taking part
Comprehensive Cancer Centers of Nevada - HendersonHenderson, Egyesült ÁllamokNo longer taking part
Oncology Las Vegas - HendersonHenderson, Egyesült ÁllamokNo longer taking part
Penn State Milton S. Hershey Medical CenterHershey, Egyesült ÁllamokNo longer taking part
Essentia Health Hibbing ClinicHibbing, Egyesült ÁllamokNo longer taking part
Edward Hines Jr VA HospitalHines, Egyesült ÁllamokNo longer taking part
Hawaii Cancer Care Inc - Waterfront PlazaHonolulu, Egyesült ÁllamokNo longer taking part
Hawaii Cancer Care Inc-LilihaHonolulu, Egyesült ÁllamokNo longer taking part
Island UrologyHonolulu, Egyesült ÁllamokNo longer taking part
Kapiolani Medical Center for Women and ChildrenHonolulu, Egyesült ÁllamokNo longer taking part
Kuakini Medical CenterHonolulu, Egyesült ÁllamokNo longer taking part
Queen's Cancer Cenrer - POB IHonolulu, Egyesült ÁllamokNo longer taking part
Queen's Cancer Center - KuakiniHonolulu, Egyesült ÁllamokNo longer taking part
Queen's Medical CenterHonolulu, Egyesült ÁllamokNo longer taking part
Straub Clinic and HospitalHonolulu, Egyesült ÁllamokNo longer taking part
The Cancer Center of Hawaii-LilihaHonolulu, Egyesült ÁllamokNo longer taking part
University of Hawaii Cancer CenterHonolulu, Egyesült ÁllamokNo longer taking part
CHI Saint Vincent Cancer Center Hot SpringsHot Springs, Egyesült ÁllamokNo longer taking part
Novant Health Cancer Institute - HuntersvilleHuntersville, Egyesült ÁllamokNo longer taking part
Novant Health Presbyterian Medical Center HuntersvilleHuntersville, Egyesült ÁllamokNo longer taking part
Cleveland Clinic Cancer Center IndependenceIndependence, Egyesült ÁllamokNo longer taking part
IRMC Cancer CenterIndiana, Egyesült ÁllamokNo longer taking part
Indiana University/Melvin and Bren Simon Cancer CenterIndianapolis, Egyesült ÁllamokNo longer taking part
Swedish Cancer Institute-IssaquahIssaquah, Egyesült ÁllamokNo longer taking part
Essentia Health - Jamestown ClinicJamestown, Egyesült ÁllamokNo longer taking part
MU Health Care Goldschmidt Cancer CenterJefferson City, Egyesült ÁllamokNo longer taking part
Jefferson HospitalJefferson Hills, Egyesült ÁllamokNo longer taking part
University of Wisconsin Carbone Cancer Center - Johnson CreekJohnson Creek, Egyesült ÁllamokNo longer taking part
UPMC-Johnstown/John P. Murtha Regional Cancer CenterJohnstown, Egyesült ÁllamokNo longer taking part
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - JonesboroJonesboro, Egyesült ÁllamokNo longer taking part
Freeman Health SystemJoplin, Egyesült ÁllamokNo longer taking part
Mercy Hospital JoplinJoplin, Egyesült ÁllamokNo longer taking part
CHI Health Good SamaritanKearney, Egyesült ÁllamokNo longer taking part
Ochsner Medical Center KennerKenner, Egyesült ÁllamokNo longer taking part
Aurora Cancer Care-Kenosha SouthKenosha, Egyesült ÁllamokNo longer taking part
Novant Health Cancer Institute - KernersvilleKernersville, Egyesült ÁllamokNo longer taking part
Greater Dayton Cancer CenterKettering, Egyesült ÁllamokNo longer taking part
Kettering Medical CenterKettering, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-Kewanee ClinicKewanee, Egyesült ÁllamokNo longer taking part
AdventHealth KissimmeeKissimmee, Egyesült ÁllamokNo longer taking part
Providence Regional Cancer System-LaceyLacey, Egyesült ÁllamokNo longer taking part
Northwestern Medicine Lake Forest HospitalLake Forest, Egyesült ÁllamokNo longer taking part
Northwell Health/Center for Advanced MedicineLake Success, Egyesült ÁllamokNo longer taking part
CommonSpirit Saint Anthony Hospital Cancer CenterLakewood, Egyesült ÁllamokNo longer taking part
University of Michigan Health - Sparrow LansingLansing, Egyesült ÁllamokNo longer taking part
Alliance for Childhood Diseases/Cure 4 the Kids FoundationLas Vegas, Egyesült ÁllamokNo longer taking part
Comprehensive Cancer Centers of NevadaLas Vegas, Egyesült ÁllamokNo longer taking part
Comprehensive Cancer Centers of Nevada - Central ValleyLas Vegas, Egyesült ÁllamokNo longer taking part
Comprehensive Cancer Centers of Nevada - NorthwestLas Vegas, Egyesült ÁllamokNo longer taking part
Comprehensive Cancer Centers of Nevada - Town CenterLas Vegas, Egyesült ÁllamokNo longer taking part
Comprehensive Cancer Centers of Nevada-SummerlinLas Vegas, Egyesült ÁllamokNo longer taking part
OptumCare Cancer Care at CharlestonLas Vegas, Egyesült ÁllamokNo longer taking part
OptumCare Cancer Care at Fort ApacheLas Vegas, Egyesült ÁllamokNo longer taking part
OptumCare Cancer Care at MountainViewLas Vegas, Egyesült ÁllamokNo longer taking part
Radiation Oncology Centers of Nevada CentralLas Vegas, Egyesült ÁllamokNo longer taking part
Radiation Oncology Centers of Nevada SoutheastLas Vegas, Egyesült ÁllamokNo longer taking part
Dartmouth Hitchcock Medical Center/Dartmouth Cancer CenterLebanon, Egyesült ÁllamokNo longer taking part
Beebe Medical CenterLewes, Egyesült ÁllamokNo longer taking part
Geisinger Medical Oncology-LewisburgLewisburg, Egyesült ÁllamokNo longer taking part
CommonSpirit Saint Joseph Hospital - LexingtonLexington, Egyesült ÁllamokNo longer taking part
CommonSpirit Saint Joseph Medical Center - East LexingtonLexington, Egyesült ÁllamokNo longer taking part
Saint Joseph Radiation Oncology Resource CenterLexington, Egyesült ÁllamokNo longer taking part
Wilcox Memorial Hospital and Kauai Medical ClinicLihue, Egyesült ÁllamokNo longer taking part
AdventHealth LittletonLittleton, Egyesült ÁllamokNo longer taking part
Trinity Health Saint Mary Mercy Livonia HospitalLivonia, Egyesült ÁllamokNo longer taking part
Monmouth Medical CenterLong Branch, Egyesült ÁllamokNo longer taking part
Longmont United HospitalLongmont, Egyesült ÁllamokNo longer taking part
PeaceHealth Saint John Medical CenterLongview, Egyesült ÁllamokNo longer taking part
Los Angeles General Medical CenterLos Angeles, Egyesült ÁllamokNo longer taking part
USC / Norris Comprehensive Cancer CenterLos Angeles, Egyesült ÁllamokNo longer taking part
Jewish HospitalLouisville, Egyesült ÁllamokNo longer taking part
UofL Health Medical Center NortheastLouisville, Egyesült ÁllamokNo longer taking part
Lowell General HospitalLowell, Egyesült ÁllamokNo longer taking part
Henry Ford Saint John Hospital - Macomb MedicalMacomb, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-MacombMacomb, Egyesült ÁllamokNo longer taking part
University of Wisconsin Carbone Cancer Center - University HospitalMadison, Egyesült ÁllamokNo longer taking part
Southern Ocean County Medical CenterManahawkin, Egyesült ÁllamokNo longer taking part
Cleveland Clinic Cancer Center MansfieldMansfield, Egyesült ÁllamokNo longer taking part
Fairview Clinics and Surgery Center Maple GroveMaple Grove, Egyesült ÁllamokNo longer taking part
Minnesota Oncology Hematology PA-MaplewoodMaplewood, Egyesült ÁllamokNo longer taking part
Saint John's Hospital - HealtheastMaplewood, Egyesült ÁllamokNo longer taking part
Aurora Bay Area Medical Group-MarinetteMarinette, Egyesült ÁllamokNo longer taking part
Saint Mary's Oncology/Hematology Associates of MarletteMarlette, Egyesült ÁllamokNo longer taking part
Marshfield Medical Center-MarshfieldMarshfield, Egyesült ÁllamokNo longer taking part
Matthews Radiation Oncology CenterMatthews, Egyesült ÁllamokNo longer taking part
Novant Health Cancer Institute - MatthewsMatthews, Egyesült ÁllamokNo longer taking part
Hillcrest Hospital Cancer CenterMayfield Heights, Egyesült ÁllamokNo longer taking part
Loyola University Medical CenterMaywood, Egyesült ÁllamokNo longer taking part
UPMC Cancer Center at UPMC McKeesportMcKeesport, Egyesült ÁllamokNo longer taking part
Baptist Memorial Hospital and Cancer Center-MemphisMemphis, Egyesült ÁllamokNo longer taking part
Saint Luke's Cancer Institute - MeridianMeridian, Egyesült ÁllamokNo longer taking part
Mount Sinai Medical CenterMiami Beach, Egyesült ÁllamokNo longer taking part
Garnet Health Medical CenterMiddletown, Egyesült ÁllamokNo longer taking part
Beebe South Coastal Health CampusMillville, Egyesült ÁllamokNo longer taking part
Aurora Cancer Care-MilwaukeeMilwaukee, Egyesült ÁllamokNo longer taking part
Aurora Saint Luke's Medical CenterMilwaukee, Egyesült ÁllamokNo longer taking part
Aurora Sinai Medical CenterMilwaukee, Egyesült ÁllamokNo longer taking part
Abbott-Northwestern HospitalMinneapolis, Egyesült ÁllamokNo longer taking part
Health Partners IncMinneapolis, Egyesült ÁllamokNo longer taking part
Hennepin County Medical CenterMinneapolis, Egyesült ÁllamokNo longer taking part
Marshfield Medical Center - MinocquaMinocqua, Egyesült ÁllamokNo longer taking part
Saint Patrick Hospital - Community HospitalMissoula, Egyesült ÁllamokNo longer taking part
Forbes HospitalMonroeville, Egyesült ÁllamokNo longer taking part
UPMC Cancer Center - MonroevilleMonroeville, Egyesült ÁllamokNo longer taking part
UPMC Hillman Cancer Center - MonroevilleMonroeville, Egyesült ÁllamokNo longer taking part
Monticello Cancer CenterMonticello, Egyesült ÁllamokNo longer taking part
UPMC Hillman Cancer Center in CoraopolisMoon Township, Egyesült ÁllamokNo longer taking part
Novant Health Cancer Institute - MooresvilleMooresville, Egyesült ÁllamokNo longer taking part
West Virginia University HealthcareMorgantown, Egyesült ÁllamokNo longer taking part
Novant Health Cancer Institute - Mount AiryMount Airy, Egyesült ÁllamokNo longer taking part
UPMC Hillman Cancer Center - Part of Frick HospitalMount Pleasant, Egyesült ÁllamokNo longer taking part
SSM Health Good SamaritanMount Vernon, Egyesült ÁllamokNo longer taking part
Arnold Palmer Cancer Center Medical Oncology NorwinN. Huntingdon, Egyesült ÁllamokNo longer taking part
Saint Luke's Cancer Institute - NampaNampa, Egyesült ÁllamokNo longer taking part
Vanderbilt University/Ingram Cancer CenterNashville, Egyesült ÁllamokNo longer taking part
Allegheny Valley HospitalNatrona Heights, Egyesült ÁllamokNo longer taking part
Jersey Shore Medical CenterNeptune City, Egyesült ÁllamokNo longer taking part
Baptist Memorial Hospital and Cancer Center-Union CountyNew Albany, Egyesült ÁllamokNo longer taking part
Rutgers Cancer Institute of New JerseyNew Brunswick, Egyesült ÁllamokNo longer taking part
UPMC Hillman Cancer Center - New CastleNew Castle, Egyesült ÁllamokNo longer taking part
Ochsner Medical Center JeffersonNew Orleans, Egyesült ÁllamokNo longer taking part
Cancer Center of Western WisconsinNew Richmond, Egyesült ÁllamokNo longer taking part
Laura and Isaac Perlmutter Cancer Center at NYU LangoneNew York, Egyesült ÁllamokNo longer taking part
NYP/Weill Cornell Medical CenterNew York, Egyesült ÁllamokNo longer taking part
Christiana Care Health System-Christiana HospitalNewark, Egyesült ÁllamokNo longer taking part
Delaware Clinical and Laboratory Physicians PANewark, Egyesült ÁllamokNo longer taking part
Helen F Graham Cancer CenterNewark, Egyesült ÁllamokNo longer taking part
Medical Oncology Hematology Consultants PANewark, Egyesült ÁllamokNo longer taking part
Providence Newberg Medical CenterNewberg, Egyesült ÁllamokNo longer taking part
Newport HospitalNewport, Egyesült ÁllamokNo longer taking part
Novant Health Cancer Institute - WilkesboroNorth Wilkesboro, Egyesült ÁllamokNo longer taking part
Henry Ford Health Providence Novi HospitalNovi, Egyesült ÁllamokNo longer taking part
Cancer Care Center of O'FallonO'Fallon, Egyesült ÁllamokNo longer taking part
Mercy Hospital Oklahoma CityOklahoma City, Egyesült ÁllamokNo longer taking part
Alegent Health Bergan Mercy Medical CenterOmaha, Egyesült ÁllamokNo longer taking part
Alegent Health Immanuel Medical CenterOmaha, Egyesült ÁllamokNo longer taking part
Alegent Health Lakeside HospitalOmaha, Egyesült ÁllamokNo longer taking part
Nebraska Medicine-Village PointeOmaha, Egyesült ÁllamokNo longer taking part
University of Nebraska Medical CenterOmaha, Egyesült ÁllamokNo longer taking part
AdventHealth East OrlandoOrlando, Egyesült ÁllamokNo longer taking part
AdventHealth OrlandoOrlando, Egyesült ÁllamokNo longer taking part
Vince Lombardi Cancer Clinic - OshkoshOshkosh, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-Ottawa ClinicOttawa, Egyesült ÁllamokNo longer taking part
Baptist Memorial Hospital and Cancer Center-OxfordOxford, Egyesült ÁllamokNo longer taking part
Stanford Cancer Institute Palo AltoPalo Alto, Egyesült ÁllamokNo longer taking part
VA Palo Alto Health Care SystemPalo Alto, Egyesült ÁllamokNo longer taking part
Essentia Health - Park RapidsPark Rapids, Egyesült ÁllamokNo longer taking part
AdventHealth ParkerParker, Egyesült ÁllamokNo longer taking part
Camden Clark Medical CenterParkersburg, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-PekinPekin, Egyesült ÁllamokNo longer taking part
OSF Saint Francis Radiation Oncology at PekinPekin, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-PeoriaPeoria, Egyesült ÁllamokNo longer taking part
Methodist Medical Center of IllinoisPeoria, Egyesült ÁllamokNo longer taking part
OSF Saint Francis Medical CenterPeoria, Egyesült ÁllamokNo longer taking part
OSF Saint Francis Radiation Oncology at Peoria Cancer CenterPeoria, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-PeruPeru, Egyesült ÁllamokNo longer taking part
Valley Radiation OncologyPeru, Egyesült ÁllamokNo longer taking part
University of Pennsylvania/Abramson Cancer CenterPhiladelphia, Egyesült ÁllamokNo longer taking part
Cancer Center at Saint Joseph'sPhoenix, Egyesült ÁllamokNo longer taking part
Allegheny General HospitalPittsburgh, Egyesült ÁllamokNo longer taking part
UPMC Hillman Cancer CenterPittsburgh, Egyesült ÁllamokNo longer taking part
UPMC-Magee Womens HospitalPittsburgh, Egyesült ÁllamokNo longer taking part
UPMC-Passavant HospitalPittsburgh, Egyesült ÁllamokNo longer taking part
UPMC-Saint Clair Hospital Cancer CenterPittsburgh, Egyesült ÁllamokNo longer taking part
UPMC-Saint MargaretPittsburgh, Egyesült ÁllamokNo longer taking part
UPMC-Shadyside HospitalPittsburgh, Egyesült ÁllamokNo longer taking part
West Penn HospitalPittsburgh, Egyesült ÁllamokNo longer taking part
Michigan Healthcare Professionals PontiacPontiac, Egyesült ÁllamokNo longer taking part
Trinity Health Saint Joseph Mercy Oakland HospitalPontiac, Egyesült ÁllamokNo longer taking part
MaineHealth Maine Medical Center - PortlandPortland, Egyesült ÁllamokNo longer taking part
Providence Portland Medical CenterPortland, Egyesült ÁllamokNo longer taking part
Providence Saint Vincent Medical CenterPortland, Egyesült ÁllamokNo longer taking part
Pottstown HospitalPottstown, Egyesült ÁllamokNo longer taking part
Illinois CancerCare-PrincetonPrinceton, Egyesült ÁllamokNo longer taking part
Rhode Island HospitalProvidence, Egyesült ÁllamokNo longer taking part
Saint Mary Corwin Medical CenterPueblo, Egyesült ÁllamokNo longer taking part
Aurora Cancer Care-RacineRacine, Egyesült ÁllamokNo longer taking part
Riverview Medical Center/Booker Cancer CenterRed Bank, Egyesült ÁllamokNo longer taking part
Beebe Health CampusRehoboth Beach, Egyesült ÁllamokNo longer taking part
Radiation Oncology AssociatesReno, Egyesült ÁllamokNo longer taking part
Renown Regional Medical CenterReno, Egyesült ÁllamokNo longer taking part
Saint Mary's Regional Medical CenterReno, Egyesült ÁllamokNo longer taking part
Valley Medical CenterRenton, Egyesült ÁllamokNo longer taking part
Marshfield Medical Center-Rice LakeRice Lake, Egyesült ÁllamokNo longer taking part
UT Southwestern Clinical Center at Richardson/PlanoRichardson, Egyesült ÁllamokNo longer taking part
Reid HealthRichmond, Egyesült ÁllamokNo longer taking part
VCU Massey Comprehensive Cancer CenterRichmond, Egyesült ÁllamokNo longer taking part
Virginia Cancer InstituteRichmond, Egyesült ÁllamokNo longer taking part
Presbyterian Rust Medical Center/Jorgensen Cancer CenterRio Rancho, Egyesült ÁllamokNo longer taking part
North Memorial Medical Health CenterRobbinsdale, Egyesült ÁllamokNo longer taking part
Mayo Clinic in RochesterRochester, Egyesült ÁllamokNo longer taking part
University of RochesterRochester, Egyesült ÁllamokNo longer taking part
Mercy Clinic-Rolla-Cancer and HematologyRolla, Egyesült ÁllamokNo longer taking part
Phelps Health Delbert Day Cancer InstituteRolla, Egyesült ÁllamokNo longer taking part
Mercy Cancer Center - SacramentoSacramento, Egyesült ÁllamokNo longer taking part
University of California Davis Comprehensive Cancer CenterSacramento, Egyesült ÁllamokNo longer taking part
MyMichigan Medical Center SaginawSaginaw, Egyesült ÁllamokNo longer taking part
Oncology Hematology Associates of Saginaw Valley PCSaginaw, Egyesült ÁllamokNo longer taking part
Dartmouth Cancer Center - NorthSaint Johnsbury, Egyesült ÁllamokNo longer taking part
Heartland Regional Medical CenterSaint Joseph, Egyesült ÁllamokNo longer taking part
Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, Egyesült ÁllamokNo longer taking part
Regions HospitalSaint Paul, Egyesült ÁllamokNo longer taking part
United HospitalSaint Paul, Egyesült ÁllamokNo longer taking part
Sainte Genevieve County Memorial HospitalSainte Genevieve, Egyesült ÁllamokNo longer taking part
Rowan Regional Medical CenterSalisbury, Egyesült ÁllamokNo longer taking part
Huntsman Cancer Institute/University of UtahSalt Lake City, Egyesült ÁllamokNo longer taking part
University of Utah Sugarhouse Health CenterSalt Lake City, Egyesült ÁllamokNo longer taking part
Pacific Central Coast Health Center-San Luis ObispoSan Luis Obispo, Egyesült ÁllamokNo longer taking part
Essentia Health SandstoneSandstone, Egyesült ÁllamokNo longer taking part
North Coast Cancer CareSandusky, Egyesült ÁllamokNo longer taking part
MaineHealth Cancer Care and IV Therapy - SanfordSanford, Egyesült ÁllamokNo longer taking part
MaineHealth Cancer Care Center of York CountySanford, Egyesült ÁllamokNo longer taking part
Mission Hope Medical Oncology - Santa MariaSanta Maria, Egyesült ÁllamokNo longer taking part
Lewis Cancer and Research Pavilion at Saint Joseph's/CandlerSavannah, Egyesült ÁllamokNo longer taking part
MaineHealth Maine Medical Center- ScarboroughScarborough, Egyesült ÁllamokNo longer taking part
TidalHealth Nanticoke / Allen Cancer CenterSeaford, Egyesült ÁllamokNo longer taking part
Swedish Medical Center-Ballard CampusSeattle, Egyesült ÁllamokNo longer taking part
Swedish Medical Center-First HillSeattle, Egyesült ÁllamokNo longer taking part
PeaceHealth United General Medical CenterSedro-Woolley, Egyesült ÁllamokNo longer taking part
UPMC Cancer Center at UPMC NorthwestSeneca, Egyesült ÁllamokNo longer taking part
Saint Francis Regional Medical CenterShakopee, Egyesült ÁllamokNo longer taking part
Vince Lombardi Cancer Clinic-SheboyganSheboygan, Egyesült ÁllamokNo longer taking part
Saint Joseph Medical Center Hematology and Oncology - SilverdaleSilverdale, Egyesült ÁllamokNo longer taking part
Avera Cancer InstituteSioux Falls, Egyesült ÁllamokNo longer taking part
Sanford Cancer Center Oncology ClinicSioux Falls, Egyesült ÁllamokNo longer taking part
Sanford USD Medical Center - Sioux FallsSioux Falls, Egyesült ÁllamokNo longer taking part
VCU Community Memorial Health CenterSouth Hill, Egyesült ÁllamokNo longer taking part
MaineHealth Cancer Care and IV Therapy - South PortlandSouth Portland, Egyesült ÁllamokNo longer taking part
Henry Ford Health Providence Southfield HospitalSouthfield, Egyesült ÁllamokNo longer taking part
Baptist Memorial Hospital and Cancer Center-DesotoSouthhaven, Egyesült ÁllamokNo longer taking part
Essentia Health-Spooner ClinicSpooner, Egyesült ÁllamokNo longer taking part
CoxHealth South HospitalSpringfield, Egyesült ÁllamokNo longer taking part
Mercy Hospital SpringfieldSpringfield, Egyesült ÁllamokNo longer taking part
Southern Illinois University School of MedicineSpringfield, Egyesült ÁllamokNo longer taking part
Springfield ClinicSpringfield, Egyesült ÁllamokNo longer taking part
Springfield Memorial HospitalSpringfield, Egyesült ÁllamokNo longer taking part
Springfield Regional Cancer CenterSpringfield, Egyesült ÁllamokNo longer taking part
Springfield Regional Medical CenterSpringfield, Egyesült ÁllamokNo longer taking part
Mercy Hospital Saint LouisSt Louis, Egyesült ÁllamokNo longer taking part
Mercy Hospital SouthSt Louis, Egyesült ÁllamokNo longer taking part
Missouri Baptist Medical CenterSt Louis, Egyesült ÁllamokNo longer taking part
Siteman Cancer Center at Christian HospitalSt Louis, Egyesült ÁllamokNo longer taking part
Siteman Cancer Center-South CountySt Louis, Egyesült ÁllamokNo longer taking part
Washington University School of MedicineSt Louis, Egyesült ÁllamokNo longer taking part
Saint Helena HospitalSt. Helena, Egyesült ÁllamokNo longer taking part
Novant Health Cancer Institute - StatesvilleStatesville, Egyesült ÁllamokNo longer taking part
Marshfield Medical Center-River Region at Stevens PointStevens Point, Egyesült ÁllamokNo longer taking part
Lakeview HospitalStillwater, Egyesült ÁllamokNo longer taking part
Cleveland Clinic Cancer Center StrongsvilleStrongsville, Egyesült ÁllamokNo longer taking part
Saint Vincent Hospital Cancer Center at Sturgeon BaySturgeon Bay, Egyesült ÁllamokNo longer taking part
Missouri Baptist Sullivan HospitalSullivan, Egyesült ÁllamokNo longer taking part
Aurora Medical Center in SummitSummit, Egyesült ÁllamokNo longer taking part
Essentia Health Saint Mary's Hospital - SuperiorSuperior, Egyesült ÁllamokNo longer taking part
ProMedica Flower HospitalSylvania, Egyesült ÁllamokNo longer taking part
State University of New York Upstate Medical UniversitySyracuse, Egyesült ÁllamokNo longer taking part
Northwest Medical Specialties PLLCTacoma, Egyesült ÁllamokNo longer taking part
MyMichigan Medical Center TawasTawas City, Egyesült ÁllamokNo longer taking part
Montefiore Medical Center - Moses CampusThe Bronx, Egyesült ÁllamokNo longer taking part
Montefiore Medical Center-Einstein CampusThe Bronx, Egyesült ÁllamokNo longer taking part
Montefiore Medical Center-Weiler HospitalThe Bronx, Egyesült ÁllamokNo longer taking part
Novant Health Cancer Institute - ThomasvilleThomasville, Egyesült ÁllamokNo longer taking part
ProMedica Toledo Hospital/Russell J Ebeid Children's HospitalToledo, Egyesült ÁllamokNo longer taking part
Community Medical CenterToms River, Egyesült ÁllamokNo longer taking part
Dayton Physicians LLC - TroyTroy, Egyesült ÁllamokNo longer taking part
Upper Valley Medical CenterTroy, Egyesült ÁllamokNo longer taking part
Saint Luke's Cancer Institute - Twin FallsTwin Falls, Egyesült ÁllamokNo longer taking part
Vince Lombardi Cancer Clinic-Two RiversTwo Rivers, Egyesült ÁllamokNo longer taking part
UPMC Cancer Center-UniontownUniontown, Egyesült ÁllamokNo longer taking part
UPMC Uniontown Hospital Radiation OncologyUniontown, Egyesült ÁllamokNo longer taking part
PeaceHealth Southwest Medical CenterVancouver, Egyesült ÁllamokNo longer taking part
Essentia Health Virginia ClinicVirginia, Egyesült ÁllamokNo longer taking part
Ridgeview Medical CenterWaconia, Egyesült ÁllamokNo longer taking part
Providence Saint Mary Regional Cancer CenterWalla Walla, Egyesült ÁllamokNo longer taking part
Henry Ford Health Warren HospitalWarren, Egyesült ÁllamokNo longer taking part
Saint Joseph Warren HospitalWarren, Egyesült ÁllamokNo longer taking part
South Pointe HospitalWarrensville Heights, Egyesült ÁllamokNo longer taking part
Illinois CancerCare - WashingtonWashington, Egyesült ÁllamokNo longer taking part
UPMC Cancer Center-WashingtonWashington, Egyesült ÁllamokNo longer taking part
UPMC Washington Hospital Radiation OncologyWashington, Egyesült ÁllamokNo longer taking part
MedStar Georgetown University HospitalWashington D.C., Egyesült ÁllamokNo longer taking part
Aurora Cancer Care-Milwaukee WestWauwatosa, Egyesült ÁllamokNo longer taking part
Aurora West Allis Medical CenterWest Allis, Egyesült ÁllamokNo longer taking part
Saint Mary's Oncology/Hematology Associates of West BranchWest Branch, Egyesült ÁllamokNo longer taking part
University of Cincinnati Cancer Center-West ChesterWest Chester, Egyesült ÁllamokNo longer taking part
Mercy Medical Center-West LakesWest Des Moines, Egyesült ÁllamokNo longer taking part
UPMC West Mifflin-Cancer Center JeffersonWest Mifflin, Egyesült ÁllamokNo longer taking part
Reading HospitalWest Reading, Egyesült ÁllamokNo longer taking part
Marshfield Medical Center - WestonWeston, Egyesült ÁllamokNo longer taking part
Wexford Health and Wellness PavilionWexford, Egyesült ÁllamokNo longer taking part
Presbyterian Intercommunity HospitalWhittier, Egyesült ÁllamokNo longer taking part
Rice Memorial HospitalWillmar, Egyesült ÁllamokNo longer taking part
Novant Health Forsyth Medical CenterWinston-Salem, Egyesült ÁllamokNo longer taking part
Minnesota Oncology Hematology PA-WoodburyWoodbury, Egyesült ÁllamokNo longer taking part
Woodland Memorial HospitalWoodland, Egyesült ÁllamokNo longer taking part
Cleveland Clinic Wooster Family Health and Surgery CenterWooster, Egyesült ÁllamokNo longer taking part
North Star Lodge Cancer Center at Yakima Valley Memorial HospitalYakima, Egyesült ÁllamokNo longer taking part
UPMC MemorialYork, Egyesült ÁllamokNo longer taking part
Saint Elizabeth Youngstown HospitalYoungstown, Egyesült ÁllamokNo longer taking part
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor CampusYpsilanti, Egyesült ÁllamokNo longer taking part

Trial details

Who runs it: National Cancer Institute (NCI)
Trial code: NCT03604991
Record updated: 2026. november 2.
Original description: This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. Immunotherapy with antibodies, such as nivolumab and ipilimumab, may remove the brake on the body's immune system and may interfere with the ability of tumor cells to grow and spread. Chemotherapy and radiation therapy may reduce the tumor size and the amount of normal tissue that needs to be removed during surgery. A combined treatment with nivolumab and ipilimumab, chemotherapy, and radiation therapy might be more effective in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery.Read full original descriptionShow less
A Phase II/III Study of Peri-Operative Nivolumab and Ipilimumab in Patients With Locoregional Esophageal and Gastroesophageal Junction Adenocarcinoma
This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. Immunotherapy with antibodies, such as nivolumab and ipilimumab, may remove the brake on the body's immune system and may interfere with the ability of tumor cells to grow and spread. Chemotherapy and radiation therapy may reduce the tumor size and the amount of normal tissue that needs to be removed during surgery. A combined treatment with nivolumab and ipilimumab, chemotherapy, and radiation therapy might be more effective in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery.
Inclusion: STEP 1 RANDOMIZATION: Patients must be age >= 18 years; STEP 1 RANDOMIZATION: Patients must have histologically confirmed T1N1-3M0 or T2-3N0-2M0 esophageal or gastroesophageal junctional adenocarcinoma (Siewert I and II); STEP 1 RANDOMIZATION: Patients must have an Eastern Cooperative Oncology Group (ECOG) performance status 0-1; STEP 1 RANDOMIZATION: Patents must be deemed a surgical candidate by a thoracic surgeon, surgical oncologist, or surgeon who is qualified to perform an esophagectomy; STEP 1 RANDOMIZATION: Absolute neutrophil count >= 1,500/mcL (within less than or equal to 14 days prior to randomization); STEP 1 RANDOMIZATION: Platelets >= 100,000/mcL (within less than or equal to 14 days prior to randomization); STEP 1 RANDOMIZATION: Total bilirubin =< institutional upper limit of normal (ULN) (within less than or equal to 14 days prior to randomization); STEP 1 RANDOMIZATION: Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase [SGOT])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase [SGPT]) =< 2.5 x institutional ULN (within less than or equal to 14 days prior to randomization); STEP 1 RANDOMIZATION: Serum creatinine =< 1.5 x institutional ULN (within less than or equal to 14 days prior to randomization); STEP 1 RANDOMIZATION: Hemoglobin (Hgb) >= 9 g/dL (within less than or equal to 14 days prior to randomization); STEP 1 RANDOMIZATION: Leukocytes >= 3,000/mm\^3 (within less than or equal to 14 days prior to randomization); STEP 1 RANDOMIZATION: Patients may not have received prior chemotherapy or radiation therapy for management for this malignancy; STEP 1 RANDOMIZATION: Patients may not have received prior immunotherapy for management of this malignancy or for any other past malignancy; STEP 1 RANDOMIZATION: Patients must have no contraindication to receiving either carboplatin or paclitaxel chemotherapy; STEP 1 RANDOMIZATION: Patients must have no contraindication to receiving radiation therapy; STEP 1 RANDOMIZATION: Patients with active autoimmune disease or history of autoimmune disease that might recur, which may affect vital organ function or require immune suppressive treatment including systemic corticosteroids, must be excluded. These include but are not limited to patients with a history of immune related neurologic disease, multiple sclerosis, autoimmune (demyelinating) neuropathy, Guillain-Barre syndrome, myasthenia gravis; systemic autoimmune disease such as systemic lupus erythematosus (SLE), connective tissue disease, scleroderma, inflammatory bowel disease (IBD), Crohn's, ulcerative colitis, hepatitis; and patients with a history of toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome, or phospholipid syndrome must be excluded because of the risk of recurrence or exacerbation of disease. Patients with vitiligo, endocrine deficiencies including thyroiditis managed with replacement hormones including physiologic corticosteroids are eligible. Patients with rheumatoid arthritis and other arthropathies, Sjogren's syndrome and psoriasis controlled with topical medication and patients with positive serology, such as antinuclear antibodies (ANA), anti-thyroid antibodies must be evaluated for the presence of target organ involvement and potential need for systemic treatment but should otherwise be eligible; STEP 1 RANDOMIZATION: Patients are permitted to enroll if they have vitiligo, type I diabetes mellitus, residual hypothyroidism due to autoimmune condition only requiring hormone replacement, psoriasis not requiring systemic treatment, or conditions not expected to recur in the absence of an external trigger (precipitating event); STEP 1 RANDOMIZATION: Patient must NOT have previous or concurrent malignancy. Exceptions are made for patients who meet any of the following conditions:; Non-melanoma skin cancer, in situ cervical cancer, superficial bladder cancer, or breast cancer in situ OR; Prior malignancy completely excised or removed and patient has been continuously disease free for > 5 years OR; Date of last evidence of disease; STEP 1 RANDOMIZATION: Patients must not have a condition requiring systemic treatment with either corticosteroids (> 10 mg/day prednisone equivalents) or other immunosuppressive medications within 14 days of study drug administration. Inhaled or topical steroids and adrenal replacement doses =< 10 mg/day prednisone equivalents are permitted in the absence of active autoimmune disease; STEP 1 RANDOMIZATION: Patients must have adequate cardiac function including electrocardiogram (EKG) and echocardiogram for any patient with a history of congestive heart failure (CHF) or at risk because of underlying cardiovascular disease or exposure to cardiotoxic drugs; STEP 1 RANDOMIZATION: For patients with evidence of uncontrolled CHF, myocardial infarction (MI), cardiomyopathy, or myositis, require a cardiac evaluation and clearance including lab tests and cardiology consultation (EKG, creatinine phosphokinase [CPK], troponin, and echocardiogram); STEP 1 RANDOMIZATION: Patients must not have a positive test result for hepatitis B virus surface antigen (HBV sAg) or hepatitis C virus ribonucleic acid (HCV RNA) indicating acute or chronic infection. Testing should be conducted to determine eligibility; STEP 1 RANDOMIZATION: Patients with a known history of testing positive for human immunodeficiency virus (HIV) or known acquired immunodeficiency syndrome (AIDS) must have no detectable viral load on a stable anti-viral regimen; STEP 1 RANDOMIZATION: Patients must not be receiving any other investigational agents; STEP 1 RANDOMIZATION: Patients with an uncontrolled intercurrent illness such as ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia or psychiatric illness/social situations that would limit compliance with study requirements will be excluded; STEP 1 RANDOMIZATION: Patients must not be pregnant or breast-feeding due to potential harm to an unborn fetus and possible risk for adverse events in nursing infants from carboplatin, paclitaxel, ipilimumab or nivolumab; All patients of childbearing potential must have a blood test or urine study done within 2 weeks prior to randomization to rule out pregnancy. Those enrolled on Arm B with nivolumab must agree to have a pregnancy test (minimum sensitivity 25 IU/L or equivalent units of human chorionic gonadotropin [HCG]) within 24 hours of starting nivolumab to rule out pregnancy; A patient of childbearing potential is defined as anyone, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point 2) has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months); STEP 1 RANDOMIZATION: Patients of childbearing potential must not expect to conceive children by either abstaining from sexual intercourse for the duration of their participation in the study or by agreeing to use both double barrier contraception and birth control pills or implants for at least one month prior to the start of the study drug and continuing for 5 months after the last dose of study drug. Investigators shall counsel patients of childbearing potential on the importance of pregnancy prevention and the implications of an unexpected pregnancy; STEP 2 RANDOMIZATION: Patient registration must not exceed 12 weeks from time of esophagectomy; STEP 2 RANDOMIZATION: Patients must have a post-operative ECOG performance status of 0-2; STEP 2 RANDOMIZATION: Absolute neutrophil count >= 1,500/mcL (within less than or equal to 14 days prior to randomization); STEP 2 RANDOMIZATION: Platelets >= 100,000/mcL (within less than or equal to 14 days prior to randomization); STEP 2 RANDOMIZATION: Total bilirubin =< institutional upper limit of normal (ULN) (within less than or equal to 14 days prior to randomization); STEP 2 RANDOMIZATION: AST (SGOT)/ ALT (SGPT) =< 2.5 x institutional ULN (within less than or equal to 14 days prior to randomization); STEP 2 RANDOMIZATION: Serum creatinine =< 1.5 x institutional ULN (within less than or equal to 14 days prior to randomization); STEP 2 RANDOMIZATION: Patients must be disease free following esophagectomy as is demonstrated by having no evidence of disease on a post-surgical CT scan. Patients must also have a negative surgical margin (R0 resection); STEP 2 RANDOMIZATION: Patients must not have an active, known or suspected autoimmune disease or a condition requiring treatment with steroids or immunosuppressive agents. Patients are permitted to enroll if they have vitiligo, type I diabetes mellitus, residual hypothyroidism due to autoimmune condition only requiring hormone replacement, psoriasis not requiring systemic treatment, or conditions not expected to recur in the absence of an external trigger; STEP 2 RANDOMIZATION: Patients must not have a condition requiring systemic treatment with either corticosteroids (> 10 mg/day prednisone equivalents) or other immunosuppressive medications with 14 days of study drug administration. Inhaled or topical steroids and adrenal replacement doses > 10 mg/day prednisone equivalents are permitted in the absence of active autoimmune disease; STEP 2 RANDOMIZATION: Patients must not be receiving any other investigational agents; STEP 2 RANDOMIZATION: Patients with an uncontrolled intercurrent illness such as ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia or psychiatric illness/social situations that would limit compliance with study requirements will be excluded; STEP 2 RANDOMIZATION: Patients must not be pregnant or breast-feeding due to potential harm to an unborn fetus and possible risks for adverse events in nursing infants from nivolumab or ipilimumab; All patients of childbearing potential must have a blood test or urine study done (minimum sensitivity 25 IU/L or equivalent units of HCG) within 2 weeks prior to randomization to rule out pregnancy. All patients must also agree to have a pregnancy test (minimum sensitivity 25 IU/L or equivalent units of HCG) within 24 hours of starting nivolumab to rule out pregnancy. Those enrolled on Arm D with ipilimumab must agree to have pregnancy tests within 72 hours of each ipilimumab administration to rule out pregnancy; STEP 2 RANDOMIZATION: Patients of childbearing potential must not expect to conceive children by either abstaining from sexual intercourse for the duration of their participation in the study or by agreeing to use both double barrier contraception and birth control pills or implants for at least one month prior to the start of the study drug and continuing for 5 months after the last dose of study drug. Investigators shall counsel patients of childbearing potential on the importance of pregnancy prevention and the implications of an unexpected pregnancy.
ClinicalTrials.gov NCT03604991