Intralipid Versus SMOFlipid in HPN Patients

Korábbi kezelés

• Patients who have previous proven addiction and dependence to alcohol/ heavy alcohol AND consumption/active use reported during last 12 months.
• Patients who have received Smoflipid greater than 4 weeks in the last 12 months prior to enrollment.
• Patients who have been on TPN greater than 4 weeks in the last 12 months prior to enrollment.

Más betegség

• Failure to provide consent
• Patients with active malignancy
• Known hypersensitivity to fish, egg, soybean, or peanut protein, or to any of the active ingredients or excipients in Smoflipid
• Patients who have active infection (as determined by the clinician) at the time of enrollment.

Laborértékek

• Severe hyperlipidemia or severe disorders of lipid metabolism with serum triglycerides more than 1,000 mg/dL.

Életkor

• Age less than 18 years

Egyéb

• Pregnant and lactating women
• Patients with underlying liver dysfunction (defined as liver function studies equal to or more than 2 times upper limit of normal) or pathology as determined by primary investigator
• Patients who are deemed to be on HPN for less than three months
• Patients who will not be managed by the Mayo Clinic HPN team
• Enrolled in another interventional study.

• Newly initiated Mayo Clinic HPN patient
• Able to provide informed consent
• Anticipated duration of HPN greater than 3 months,
• Infusion company is able to provide Smoflipid