NCT03783143Befejeződött
Prevalence and Incidence of Lassa Virus Infection in Southern Mali
Serosurvey for Prevalence and Incidence of Lassa Virus Infection in Southern Mali
Forrás: ClinicalTrials.gov · Utoljára frissítve: 2026. aug. 28.
Rövid összefoglaló (regiszter, angolul)
Background: The disease Lassa fever mostly affects people in Western Africa. It is very similar to other diseases that cause fever, like malaria and yellow fever. People get Lassa fever from mice infected with Lassa virus. It can also be spread from body fluids of people with the disease. Researchers want to learn more about this virus in Mali so they can develop better tools to diagnose and prevent it. Objective: To find out how many people in certain areas of southern Mali have ever had Lassa fever and count how many people get the disease every year. Eligibility: People ages 6 months to 99 years who live in certain areas of Mali Design: Women who are could become pregnant will have a urine pregnancy test at each visit. Participants will be asked questions about their age, if they have ever had a fever, and if they have ever seen mice in or around their home. This will take about 20 minutes. Participants will give a blood sample using a needle in a vein in the arm. Young children will give it by pricking a finger or heel with a needle. Patients with a fever illness will have a medical history and physical exam. They will give blood and nasal swabs 3 times over 21 days. Participants may be asked to come back 1 time each year for up to 3 more years to take another sample of blood and answer more questions.
- Állapot (regiszter)
- Befejeződött
- Vizsgálattípus
- Megfigyeléses
- Résztvevők száma
- 8524 (tényleges)
- Első benyújtás
- 2018. dec. 19.
- Kezdés
- 2020. dec. 4.
- Elsődleges befejezés
- 2024. júl. 25.
- Fő szponzor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NCT-szám
- NCT03783143
Mit vállalsz
- Vizsgálat típusa: Megfigyeléses
- Bevont résztvevők: 8524
- 2020. dec. 4. és az elsődleges befejezés (2024. júl. 25.) között
- 1 helyszín, 1 országban
- Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket
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Más betegség
- Any condition that, in the opinion of the investigator, contraindicates participation in this study, including conditions that could hinder compliance or that could place participants or study staff at increased risk.
- Signs or symptoms of fever-associated conditions other than LF, such as urinary tract infection, or any other infection that may cause fever.
- Co-enrollment guidelines: Participants may be co-enrolled in other studies; however, study staff should be notified of co-enrollment
Egyéb
- General exclusion criteria:
- Pregnancy.
- Additional exclusion criteria for the clinic-based study (study 2):
A regiszterben nem jelölt feltételek
- INCLUSION CRITERIA:
- Age greater than or equal to 6 months to 99 years.
- Resident of one of the study sites for at least 3 months.
- Able to provide informed consent.
- Agrees to allow storage of samples for future research.
- Additional inclusion criteria for the cross-sectional study (study 1):
- No plans to relocate before the study end date.
- Additional inclusion criteria for the clinic-based study (study 2):
- Has fever (temperature greater than or equal to 38 degree celcius), or has had antecedent of fever for at least 2 consecutive days at the time of screening.
- One or more of the following:
- Excluded typhoid fever and and has at least 1 of the following symptoms: chest pain, sore throat, headache, muscle pain,vomiting, and diarrhea.
- Shows bleeding or facial edema.
- Does not respond to anti-malarials or antibiotics after 2 days of treatment.
- Had contact with a confirmed LF case within the last 3 weeks.
Életkor a regiszterben: 6 hónap – 110 év · Nem: nők és férfiak · Egészséges önkénteseket nem fogad
Helyszínek (1)
Helyszínek a regiszter sorrendjében. Ha a profilodba mented a városodat, távolság szerint rendeződnek.
| Helyszín | Város | Ország | Helyszín állapota |
|---|---|---|---|
| Icer/Mrtc/Fmos/Usttb | Bamako | Mali | Ismeretlen állapot |
Ez az oldal tájékoztatás, nem orvosi tanács. Bármely vizsgálatról az orvosoddal beszélj.