ABCSG C08-Exercise II: Trial of Endurance Exercise Following Adjuvant Chemotherapy for Colorectal Cancer

Korábbi kezelés

• current study with chemotherapy or radiation

Más betegség

• significant comorbid conditions precluding participation in a physical activity program (investigators decision)
• Regular (3-times a week) vigorous physical activity of >150 minutes (type of physical activity: bicycling, cross walking (cross trainer), jogging, walking at a brisk pace, nordic walking, cross country skiing) within the last year before diagnosis of colorectal cancer
• past or current history of other malignant neoplasms other than colorectal cancer in the last 5 years except basal cell carcinoma of the skin and/or in situ carcinoma of the cervix
• clinically significant cardiovascular disease

Egyéb

• disabled patients unable to participate in the physical activity program
• patients unwilling to complete endurance exercise or complete all questionnaires related to the study
• left bundle branch block
• current pregnancy or plans to become pregnant within the next 3 years

• completely resected, histologically confirmed adenocarcinoma of the colon or rectum
• patients, who have completed adjuvant chemotherapy 4-16 weeks prior to randomization
• Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
• Age ≥18 years
• adequate hematologic functions <=28d prior to randomization
• able to perform endurance exercise according to protocol
• ability to perform ergometry in order to assess physical capability at the discretion of the investigator
• signed informed consent prior to randomization