NCT03919760Befejeződött
Early Psychosis Intervention - Spreading Evidence-based Treatment
Enhancing Evidence-Based Practice for Youth and Emerging Adults With Early Psychosis: Implementation and Evaluation in Diverse Service Settings
Forrás: ClinicalTrials.gov · Utoljára frissítve: 2026. márc. 18.
Rövid összefoglaló (regiszter, angolul)
Implementation of 'NAVIGATE' in Ontario aims to help youth and emerging adults suffering from a first episode of psychosis. Although Ontario already has early psychosis intervention programs, the team's recent work has identified major challenges of delivering coordinated care, particularly those elements of care that enhance recovery. These challenges also exist nationally and internationally. By building on the already existing early psychosis intervention community of practice through the Early Psychosis Intervention Ontario Network, the investigators will implement NAVIGATE with the help of CAMH's Provincial System Support Program facilitators. The use of tele-videoconferencing through ECHO Mental Health Ontario and ECHO processes and protocols provide us with an opportunity to ensure sustainability. Using health administrative data held at the Institute for Clinical Evaluative Sciences (ICES), the investigators can examine system-level outcomes, including hospitalizations, emergency department visits, and outpatient physician visits of youth and emerging adults suffering from a first episode psychosis who are treated with NAVIGATE compared with those treated in early psychosis intervention programs without NAVIGATE and those who are not treated in early psychosis intervention programs. In addition, the investigators can also evaluate health care costs. Prior to initiating this project, the investigators obtained the input of youth and emerging adults with a first episode psychosis and family members. The investigators will also continue to measure engagement across the study. Hypotheses: 1. Following the implementation of NAVIGATE, program fidelity (i.e. adaptability) to the Ontario early psychosis intervention standard will improve. 2. Compared to patients not receiving NAVIGATE, those who receive NAVIGATE through this implementation study will have fewer days in hospital, fewer emergency department visits, fewer suicide attempts, lower mortality, and lower healthcare costs. 3. Improvements in functioning and symptoms will be comparable to the RAISE study (an earlier study assessing NAVIGATE); improvement may be influenced by demographic, socio-economic, geographic, and clinical factors. 4. The project's engagement approach will demonstrate that the investigators used the full range of patient engagement based on objectively assessed engagement metrics.
- Állapot (regiszter)
- Befejeződött
- Vizsgálattípus
- Beavatkozással járó
- Résztvevők száma
- 100 (tényleges)
- Első benyújtás
- 2019. márc. 19.
- Kezdés
- 2020. jan. 3.
- Elsődleges befejezés
- 2024. dec. 23.
- Fő szponzor
- Centre for Addiction and Mental Health
- Betegségek
- Skizofrénia, Bipoláris zavar
- NCT-szám
- NCT03919760
Mit vállalsz
- Vizsgálat típusa: Beavatkozással járó
- Bevont résztvevők: 100
- 2020. jan. 3. és az elsődleges befejezés (2024. dec. 23.) között
- 6 helyszín, 1 országban
- Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket
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Egyéb
- Absence of psychosis
- Inability to provide informed consent to participate in the research study
A regiszterben nem jelölt feltételek
- Early psychosis intervention (EPI) programs from specific geographic regions of Ontario will be included. Investigators will recruit consecutive referrals to the EPI programs participating in the study. All of the EPI sites follow people experiencing a first episode psychosis.
- Individual inclusion criteria:
- Age range of 14-35 years;
- any DSM-diagnosis that can manifest as early psychosis (schizophrenia, schizoaffective disorder, schizophreniform disorder, bipolar I disorder, major depressive disorder with psychotic features, substance induced psychotic disorder, or unspecified psychotic disorder);
Életkor a regiszterben: 14 év – 35 év · Nem: nők és férfiak · Egészséges önkénteseket nem fogad
Helyszínek (6)
Helyszínek a regiszter sorrendjében. Ha a profilodba mented a városodat, távolság szerint rendeződnek.
| Helyszín | Város | Ország | Helyszín állapota |
|---|---|---|---|
| Health Sciences North | Greater Sudbury | Kanada | Ismeretlen állapot |
| North Bay Regional Health Centre | North Bay | Kanada | Ismeretlen állapot |
| Durham Amaze- Lakeridge Health | Oshawa | Kanada | Ismeretlen állapot |
| Niagara Region Public Health | Thorold | Kanada | Ismeretlen állapot |
| First Place Clinic and Regional Resource Centre | Thunder Bay | Kanada | Ismeretlen állapot |
| CMHA Waterloo Wellington | Waterloo | Kanada | Ismeretlen állapot |
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