Lidocaine Infusion in Pancreatic Cancer

Korábbi kezelés

• Is currently being treated with any of the following class I antiarrhythmic drugs; quinidine, flecainide, disopyramide, or procainamide
• Has been treated with amiodarone in the past

Más betegség

• Has hypersensitivity or allergy to amide-linked local anesthetics
• Has a second or third degree heart block
• Has Adams-Stoke syndrome
• Has Wolff-Parkinson-White syndrome
• Has a history of blood clots, pulmonary embolism, or deep vein thrombosis unless controlled by anticoagulant treatment
• Has a known history of human immunodeficiency virus (HIV) positivity or untreated and uncontrolled hepatitis B or C

Egyéb

• Has American Society of Anesthesiologists (ASA) physical status > 3
• Has severe sinoatrial block

• Has histologically or cytologically confirmed adenocarcinoma of the pancreas that is considered resectable as well as other types of pancreatic cancer (malignant endocrine and exocrine tumors)
• Has measurable disease, defined as at least 1 tumor that fulfills the criteria
• Patients diagnosed with resectable cancer, but upon initial phase of surgical exploration found to have metastatic disease
• Has read, understood and signed the informed consent form (ICF) approved by the Independent Review Board/Independent Ethics Committee (IRB/IEC)
• Prior systemic treatments for metastatic disease are permitted, including targeted therapies, biologic response modifiers, chemotherapy, hormonal therapy, or investigational therapy.