Using Early Time Restricted Feeding and Timed Light Therapy to Improve Glycemic Control in Adults With Type 2 Diabetes

Korábbi kezelés

• Change in the dosage of a chronic medication within the past month (need to wait at least 1 month prior to baseline visit)
• Lost or gained more than 8 lbs within the last 2 months and weight needs to be stable for a minimum of 4 weeks before baseline testing
• Traveled more than two times zones away in the two months prior to enrolling in the trial or will travel more than two time zones away during the 16-week study

Más betegség

• On insulin or diabetes medication other than metformin, DPP-IV inhibitors, SGLT2 inhibitors, sulfonylureas, and/or GLP-1 receptor agonists
• Moderate or severe retinopathy or other medical condition that may affect the ability to safely receive bright light therapy
• A history of severe hypoglycemia
• Severe gastrointestinal disease, major gastrointestinal surgery, or active gallstone disease
• Cardiovascular, renal, cardiac, liver, lung, adrenal, or nervous system disease that is unstable or may compromise study validity
• Evidence of cancer (other than non-melanoma skin cancer) within the last 5 years
• Current diagnosis of a major psychiatric condition that would impair study participation
• Diagnosed sleep disorder or circadian disorder that is not stabilized (sleep apnea is allowed). Those with narcolepsy will not be included.

Laborértékek

• Have a clinically significant laboratory abnormality (e.g., abnormal hemoglobin levels)

Életkor

• Have type 1 diabetes or was diagnosed with diabetes before age 18

Egyéb

• Pregnant or breastfeeding
• Major changes in health or medical history in the last 3 months that could affect data validity per judgement of the study physician
• Spend an average of more than 1.5 hours/day outdoors
• Perform overnight shift work more than 1 day/week on average
• Regularly eat within a less than a 10-hour period daily
• Regularly finish eating dinner before 6:30 pm

• Aged 30-80 years old
• Have type 2 diabetes
• HbA1c between 5.7 - 12.0%
• On a stable dose of metformin, DPP-IV inhibitors, SGLT2 inhibitors, sulfonylureas, and/or GLP-1 receptor agonists for at least 6 weeks, or taking no diabetes medications
• Wake up at a regular time between 5-9 am