Fluorescence-guided Surgery Using cRGD-ZW800-1 in Oral Cancer

Korábbi kezelés

• Previous surgery, chemotherapy or radiotherapy to the oral cavity;
• Patients with a previous kidney transplantation in the medical history;
• Immuno-compromised patients who do not have the ability to respond normally to an infection due to an impaired on weakened immune system, caused by either a pre-existing disease or concomitant medications;

Más betegség

• History of a clinically significant allergy or anaphylactic reactions to any of the components of the agent.
• Any condition that the investigator considers to be potentially jeopardizing the patient's well-being or the study objectives.

Laborértékek

• Patients with renal insufficiency (eGFR<60);

Egyéb

• Patients pregnant or breastfeeding, lack of effective contraception in male or female patients with reproductive potential;

• Patients with biopsy-proven squamous cell carcinoma of the oral cavity, eligible for surgical resection of the primary tumor;
• ≥ 18 years of age;
• Before patient registration, written informed consent must be given according to ICH/GCP, and national/local regulations;
• Screening ECG and clinical laboratory test results are within normal limits, or if any are outside of normal limits they are considered to be clinically insignificant.