Aspirin Use for Gastric Cancer Prevention in the Early Gastric Cancer Patients

Korábbi kezelés

• Patients who received aspirin for the secondary prevention of cardiovascular diseases or cerebrovascular diseases
• Regular aspirin uses (more than 3 times a week) with 2 months before screening visit
• Patients who used anticoagulants or antiplatelet drugs for therapeutic purpose
• Previous gastrectomy history
• Alcoholism, drug abuse
• Patients who took a 28-day run-in-period medication less than 80%

Más betegség

• Current treatment for serious medical condition which could hinder participation (such as severe heart dysfunction, liver cirrhosis, renal failure, COPD or bronchial asthma, or uncontrolled infection)
• High risk patients for bleeding complications (cerebral aneurysm, vascular malformation, esophageal or gastric varices, or hemophilia, etc)
• Active peptic ulcer disease (patients who treated peptic ulcer completely could be enrolled)
• Diagnosis and active treatment for other organ cancer (except carcinoma in situ, and non-melanoma skin cancer) within 5 years
• Non-curative resection of early gastric cancer after endoscopic resection
• Aspirin allergy or contraindication of aspirin use

Egyéb

• Pregnant or lactating women
• Inadequate patients for study enrollment according to the evaluation of the study physician
• Inability to provide an informed consent

• Men and women aged 19-70 years who underwent endoscopic resection for high-grade adenoma or early gastric cancer (category 4 [non-invasive high grade neoplasm] or category 5 [invasive neoplasia] according to the Vienna classification of gastrointestinal epithelial neoplasia [Schlemper RJ, et al. Gut 2000;47:251-255.])
• Final pathological results after endoscopic resection met the absolute or expanded criteria according to the Japanese Gastric Cancer Treatment guideline 2014 (version 4)
• Patients who had negative H. pylori status or those who eradicated H. pylori status
• Willingness to sign an informed consent form