Sedentary Behavior in Older Women With and Without Type 2 Diabetes

Korábbi kezelés

• Use of hormone replacement therapy (e.g., estrogen, progesterone, testosterone) (within the past 5 years)
• Taking insulin, thiazolidinediones (e.g., rosiglitazone), glucagon-like peptide-1 (GLP1) agonists (e.g., exenatide), dipeptidyl peptidase-4 (DPP4) inhibitors (e.g., sitagliptin) or any medication for the treatment of T2D other than those listed above in the inclusion criteria

Más betegség

• Type 1 diabetes
• Uncontrolled hypertension at rest (systolic \>160 or diastolic \>110 mmHg)
• Obstructive pulmonary disease or asthma with a forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) ratio \<70% of predicted
• Any of the following conditions:
• Unstable angina
• Recent myocardial infarction, cardiac surgery, or vascular surgery (\<3 months)
• Heart failure
• Peripheral artery disease (based on report of symptomatic claudication or ankle brachial index testing)
• Hepatic or renal disease
• Severe arthritis or mobility impairment that would interfere with exercise testing
• Dementia or evidence of cognitive impairment (Mini-Cog score \< 3)

Laborértékek

• Control participants only - HbA1C ≥ 5.7%
• Use of beta blockers or centrally-acting calcium channel blockers (i.e., diltiazem, verapamil) due to potential blunting of cardiorespiratory fitness assessments
• Uncontrolled T2D (HbA1C \>9.0%)
• Anemia (tHb \<10 mg/dL)

Életkor

• Age \<60 or \>75 years

Egyéb

• Male
• Current tobacco or marijuana use or nicotine use within the last year
• Engaging in \>150 minutes/week of moderate to vigorous physical activity (assessed via Low-Level Physical Activity Recall questionnaire)

• Female
• Age 60-75 years
• Postmenopausal (self-reported)
• BMI between 25-40 kg/m2
• Participants with T2D:
• T2D confirmed via chart review
• T2D diet controlled or treated with the following acceptable medication treatments: metformin, sulfonylureas, glinides, or glucose absorption blockers