Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders

Korábbi kezelés

• Neurologic disorder, prior neurosurgical procedure, prior electroconvulsive therapy (ECT) or TMS, history of seizures or head trauma.
• Presence of metallic implants that would interfere with safety during fMRI scanning.
• Medication instability (<3 months).
• Neurologic disorder, prior neurosurgical procedure, prior ECT or TMS, history of seizures or head trauma.
• Presence of metallic implants that would interfere with safety during fMRI scanning.

Más betegség

• Current or history of psychiatric disorders
• Current or history of: organic mental disorder; substance abuse within the past 12 months and/or history of substance abuse for > 1 year; past or current substance dependence (including alcohol); schizophrenia; delusional disorder; and psychotic disorders.
• Medical illness or non-psychiatric medical treatment that would likely interfere with study participation
• Current or history of: organic mental disorder; substance abuse within the past 12 months and/or history of substance abuse for > 1 year; past or current substance dependence (including alcohol), verified by urine toxicology screen; schizophrenia; delusional disorder; and psychotic disorders.
• Medical illness or non-psychiatric medical treatment that would likely interfere with study participation

Egyéb

• Endorsement of clinical levels of emotion dysregulation
• Current pregnancy.
• Current symptoms of mania or depression (YMRS score >12, HAM-D-17 score >10).
• Current pregnancy.

• Male or female age 18-55
• No history of psychiatric disorder, as assessed using the Mini-International Neuropsychiatric Interview (MINI).
• Non-Clinical Levels of Emotion Dysregulation, as assessed using the Difficulties in Emotion Regulation Scale (DERS) Non-clinical levels of emotion dysregulation will be defined as a score < 80 on the DERS.
• Male or female age 18-55
• Diagnosis of Bipolar I Disorder (BD-I), as assessed through MINI.
• Current mood state euthymic.
  • Hamilton-Depression Rating Scale (HAM-D-17) and Young Mania Rating Scale (YMRS) will be used to assess current depressive and manic symptoms. Euthymia will be defined as a HAM-D-17 score <10 and YMRS score <12.
• Clinical Levels of Emotion Dysregulation, as assessed using the DERS. Clinical levels of emotion dysregulation will be defined as a score > 80 on the DERS.