Comparison Between Upgraded '2C3L' vs. PVI Approach for Catheter Ablation of Persistent Atrial Fibrillation

Korábbi kezelés

• patients with triple (aspirin, clopidogrel and OAC) or dual (clopidogrel and OAC) antithrombotic therapy which predispose patients to higher risk of periprocedural bleeding. (e.g., Coronary percutaneous transluminal coronary angioplasty (PTCA)/stenting within the previous 90 days),
• patients cannot be removed from antiarrhythmic drugs for reasons other than AF.

Más betegség

• patients with contraindication to right or left sided heart catheterization,
• life expectancy less than 1 year (advanced malignant tumor, end stage renal disease, etc.),

Laborértékek

• left ventricular ejection fraction (LVEF) \< 30%,

Egyéb

• patients with paroxysmal AF,
• patients with AF secondary to an obvious reversible cause,
• patients with left atrial diameter ≥ 60 mm in the parasternal long axis view,
• patients with contraindication to anticoagulation,
• pregnancy,

• Patients must meet all the following criteria to be included in the study:
• age between 18 and 80,
• patients undergoing a first-time ablation procedure for non-valvular AF,
• patients with defined as a sustained episode more than 3 months
• PeAF documented by ECG, Holter, loop recorder, telemetry, trans-telephonic monitor or implanted device within 90 days6 months of the ablation procedure,
• patients experienced symptoms caused by AF and these symptoms include but are not limited to palpitations, presyncope, syncope, fatigue, and shortness of breath,
• AF refractory to at least one AAD,
• willingness, ability and commitment to provide informed consent and participate in follow-up evaluations.