The Impact TDCS-linked Motor and Cognitive Training Gains in Parkinson's Disease

Korábbi kezelés

• undergoing physical therapy at another location
• chemical scalp treatment within the previous 30 days, and experiencing severe pain and/or discomfort that precludes performing the proposed activities.

Más betegség

• be diagnosis of atypical Parkinson's disease
• neuropsychiatric comorbidities; convulsions, metal clips and/or pacemaker; deep brain stimulation implant; history of epilepsy; neurosurgery; traumatic brain injury; alcohol abuse or drug dependency;
• associated diseases of the peripheral or central nervous system

Egyéb

• inability to walk 10 meters
• presence of important dyskinesia that prevents the participant from sitting in a chair
• abnormal and persistent increase in systemic blood pressure before or during training, after 3 measurements taken 5 minutes apart - Cut-off: systolic blood pressure ≥ 140 mm Hg and/or diastolic ≥ 90 mm Hg
• not understanding any of the training protocol stages

• being diagnosed with idiopathic Parkinson's disease by a neurologist based on definitive evidence of responsiveness to levodopa at the start of the disease and the history of progressive hypokinesia with asymmetric onset. PD will be diagnosed based on Parkinson's Disease Society Brain Bank (PDSBB) criteria, as described in Hughes et al.
• age between 40 and 70 years, with no distinction for sex, schooling level or other sociodemographic characteristics
• disease staging between 1.5 and 3, according to the modified Hoehn and Yahr scale
• undergoing regular pharmacological treatment with levodopa (equivalent dose > 300mg) or taking antiparkinsonian medication such as anticholinergics, selegiline, dopamine agonists (amantadine) and COMT (catechol-O-methyl transferase) inhibitors
• score of more than 24 points on the Mini-Mental State Examination
• not exhibiting other associated neurological diseases and no musculoskeletal and/or cardiorespiratory changes that could compromise gait.