68Ga-HA-DOTATATE Imaging of Suspected Somatostatin Receptor Positive Tumors
Key facts
- Where
- Edmonton, KanadaSee the site
- Phase
- 2. fázis
Where in Kanada
- University of AlbertaEdmonton, KanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Alberta
- Trial code
- NCT04888481
- Record updated
- 2026. május 11.
- Original description
Somatostatin receptor (SSR) imaging is a critical component of clinical care for many patients being investigated for or with confirmed SSR positive tumors. In the past, 111In-octreotide imaging has been used for this purpose but it has been recently supplanted globally by SSR positron emission tomography (PET) imaging due to better image quality and higher diagnostic accuracy.Read full original descriptionShow less
Somatostatin receptor (SSR) imaging is a critical component of clinical care for many patients being investigated for or with confirmed SSR positive tumors. In the past, 111In-octreotide imaging has been used for this purpose but it has been recently supplanted globally by SSR positron emission tomography (PET) imaging due to better image quality and higher diagnostic accuracy.
This study will assess the safety and diagnostic effectiveness of 68Ga-HA-DOTATATE produced a the Edmonton Radiopharmaceutical Centre (ERC).
Inclusion: Patients with known or clinically suspected somatostatin receptor positive tumors including but not limited to: gastrointestinal neuroendocrine tumors, pancreatic neuroendocrine tumors, pulmonary neuroendocrine tumors, neuroendocrine tumors - primary unknown, pheochromocytoma, paraganglioma, medullary thyroid cancer, medulloblastoma, meningioma; A standard clinical CT or MRI is obtained within 6 months of enrollment; Ability to provide written informed consent prior to participation in the study (participant or if required a legal medical decision maker).
Exclusion: Previous allergic reaction to DOTATATE or somatostatin analogues; Any additional medical condition, serious inter-current illness, or other extenuating circumstance that, in the opinion of the investigator or attending department physician, may significantly interfere with study performance or interpretation; Weight > 225 kg (weight limit of the PET/CT scanner); Inability to scan (ie. extreme claustrophobia) or inability to lie still for imaging; Lack of intravenous access.