Thrombo-inflammation Biomarkers Trial in Acute Cerebral Hypoxia

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• Patients diagnosed with an acute non-vascular neurological pathology (migraine, epilepsy, etc.).

Egyéb

• Pre-existing functional and/or cognitive disability
• Patient under legal protection.
• Pregnant or breastfeeding woman.
• Patient with secondary haemorrhagic transformation.
  • Secondary exclusion criteria :
• Patients with an ischaemic lesion visible on imaging, unrelated to large vessel occlusion and therefore ineligible for mechanical thrombectomy.
• TIA patients presenting an abnormality on follow-up imaging 24-48 hours after the initial imaging.
  • Excluded patients will be replaced.

• For cases, admitted within the first 36 hours of an acute neurological symptom related to :
• An ischaemic cerebrovascular accident (iCVA) eligible for a mechanical thrombectomy procedure,
• A subarachnoid haemorrhage (SAH, all aetiologies) : patient presenting with at least a modified Fisher scale 3 or 4,
• An intra-parenchymal haematoma (IPH) with greatest axis ≥ 20mm or with NIHSS on admission >4.
  • OR
• For control patients, admitted within 7 days of the onset of acute neurological symptomatology related to a clinical diagnosis of transient ischaemic attack (TIA) - based on thorough questioning of the patient on admission - and prior to imaging, with an ABCD2≥ 2 score.
• Express consent to participate in the study.
• Member or beneficiary of a social security.