NCT05269888Fut, nem toboroz
Covid-19 Vaccine Immune Response in Multiple Sclerosis
An Observational Study to Evaluate Immune Response to Covid-19 Vaccines, Infections and Immune Treatments in People With Multiple Sclerosis
Forrás: ClinicalTrials.gov · Utoljára frissítve: 2025. febr. 4.
Rövid összefoglaló (regiszter, angolul)
Coronavirus (Covid-19) has affected millions of people worldwide. Vaccines to prevent Covid-19 infection have been offered to reduce the risk of infection. While these vaccines have been offered to people with multiple sclerosis (MS), they have not been tested in these individuals. It is uncertain whether people with MS will develop protective antibodies after a Covid-19 vaccination and how long these antibodies will last. The investigators are planning to study the immune response to the full course of Covid-19 vaccine in people with MS (study group) and compare this to people without MS or immune suppression (control group).
- Állapot (regiszter)
- Fut, nem toboroz
- Vizsgálattípus
- Megfigyeléses
- Résztvevők száma
- 240 (tervezett)
- Első benyújtás
- 2022. márc. 2.
- Kezdés
- 2022. febr. 16.
- Elsődleges befejezés
- 2024. dec. 30.
- Fő szponzor
- University Hospitals of North Midlands NHS Trust
- Betegségek
- Sclerosis multiplex (SM)
- NCT-szám
- NCT05269888
Mit vállalsz
- Vizsgálat típusa: Megfigyeléses
- Tervezett résztvevők: 240
- 2022. febr. 16. és az elsődleges befejezés (2024. dec. 30.) között
- 1 helyszín, 1 országban
- Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket
A(z) ClinicalTrials.gov regisztermezőiből összeállítva. A vizsgálat felépítését írja le.
Ki nem vehet részt
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Más betegség
- Has declined or does not wish to have Covid-19 vaccine
- Has switched DMT since the date of first dose of Covid-19 vaccine
- Has any other immunological condition or on immune treatment causing immune suppression
- Has declined or does not wish to have Covid-19 vaccine
- Ineligible* for Covid-19 vaccine (*Ineligible for health reasons and/or as per Government prioritisation of vaccinations)
- Has declined or does not wish to have Covid-19 vaccine
- Has MS or another long-term immunological condition
- History of taking any immune treatment causing immune suppression in the last 5 years
- History of any immune conditions or comorbidities known to result in immune suppression within the last 5 years;
- Ineligible* for Covid-19 vaccine (*Ineligible for health reasons and/or as per Government prioritisation of vaccinations)
Egyéb
- Non-English speaker where translation facilities are insufficient to guarantee informed consent
- Currently participating in one or more interventional trials involving immune suppression or immune agent
- Non-English speaker where translation facilities are insufficient to guarantee informed consent
Kiket keres a vizsgálat
- Aged 18 years and over
- Diagnosis of Multiple Sclerosis as per McDonald's Criteria 2017
- Falls into one of following the Disease Modification Treatment (DMT) groups: on Ocrelizumab, on Natalizumab, on Alemtuzumab, on Tecfidera, on Fingolimod, on Interferon, not on any DMT
- Has had a complete course of Covid-19 vaccination including any boosters (standard dosing: prescribed as per the UK Government guidelines)
- Willing and able to give fully informed consent
- Willing and able to comply with the study procedures
- Aged 18 years and over
- Has had a complete course of Covid-19 vaccination (standard dosing: prescribed as per the UK Government guidelines)
- Willing and able to give fully informed consent
- Willing and able to comply with the study procedures
Életkor a regiszterben: 18 év – - · Nem: nők és férfiak · Egészséges önkénteseket is fogad
Helyszínek (1)
Helyszínek a regiszter sorrendjében. Ha a profilodba mented a városodat, távolság szerint rendeződnek.
| Helyszín | Város | Ország | Helyszín állapota |
|---|---|---|---|
| University Hospitals of North Midlands NHS Trust | Stoke-on-Trent | Egyesült Királyság | Ismeretlen állapot |
Ez az oldal tájékoztatás, nem orvosi tanács. Bármely vizsgálatról az orvosoddal beszélj.