Neuroplasticity in Parkinson's Disease

Korábbi kezelés

• Intracranial metallic or magnetic devices (e.g. cochlear implant, deep brain stimulator)

Más betegség

• Dementia diagnosis and/or a University of California Brief Assessment of Capacity to Consent (UBACC) score and MacCAT-CR score indicating impaired capacity to consent
• History of musculoskeletal disorders that significant affect movement of lower or upper limbs as determined at the time of enrollment
• History of bipolar disorder, post-traumatic stress disorder or major depressive disorder
• Other significant neurological disorders that may affect participation or performance in the study
• History of seizures, epilepsy, stroke, multiple sclerosis, or traumatic brain injury
• Recent history of frequent syncope (fainting) episodes in response to blood, emotional stress, or sensory triggers.
• History of surgery on blood vessels, brain, or heart
• Severe hearing impairment

Egyéb

• Implanted DBS or other neurosurgeries to treat PD
• Pregnancy
  • Additional exclusion criteria for TMS experiments (note that individuals who are excluded from the TMS experiment still have the opportunity to participate in the other data collection sessions):
• Pacemaker or any implanted device
• Unexplained, recurring headaches or concussion within the last six months

• Participants with PD
• Diagnosis of idiopathic PD, as determined by a movement disorders neurologist in accordance with the PD Society Brain Bank diagnostic criteria
• Not receiving levodopa or dopamine agonist to treat PD (at baseline)
• Able to ambulate independently without the use of an assistive device (e.g. cane) for 50 meters Healthy Controls
• Age- (+/- 3 years) and sex-matched to participants with PD
• Able to ambulate independently without the use of an assistive device (e.g. cane) for 50 meters