Effect of NMN (Nicotinamide Mononucleotide) on Polycystic Ovary Syndrome

Korábbi kezelés

• Individuals who currently receiving weight-loss drugs or surgery or within the past 2 months.
• Use of medications that affect hormone levels, appetite, carbohydrate absorption, and metabolism within the past 2 months.

Más betegség

• Individuals who suffering from other diseases that may cause hyperandrogenism and ovulation abnormalities.
• Individuals who need regular medication to treat chronic diseases such as diabetes, hypertension, gout, hyperuricemia, etc.
• Individuals with severe liver diseases or kidney disease that are ineligible to participate in the study.
• A medical history of severe cardiovascular and cerebrovascular diseases.
• Individuals who currently suffer from severe gastrointestinal diseases or undergo gastrointestinal resection that may affect nutrient absorption.
• Individuals who need drug treatment for any mental illness such as epilepsy and depression.
• Cancer patients.
• Individuals who suffer from infectious diseases such as hepatitis B, active tuberculosis, AIDS, etc.

Egyéb

• Individuals who are during pregnant, lactation or menopause.
• Individuals who take niacin, nicotinamide, or other vitamin B-related supplementation currently or within the past 2 months.
• Individuals who drink more than 15g of alcohol per day or have a smoking habit.

• Individuals who are 20 to 40 years old;
• BMI < 25 kg/m2;
• Individuals with PCOS should meet all the Rotterdam diagnostic criteria: 1) Oligo- and/or anovulation; 2) Clinical and/or biochemical signs of hyperandrogenism; 3) Polycystic ovaries, and exclusion of other aetiologies (congenital adrenal hyperplasia, androgen-secreting tumors, Cushing's syndrome).
• Individuals who can insist on continuous monitoring in the outpatient clinic.
• Individuals who are not participating in other research projects currently or 3 months before the intervention.