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NCT05775835Befejeződött

Effects of Whole Body Vibration and Resistance Exercise on Carotis Intima Media and Muscle Architecture in Hypertension

Effects of Whole Body Vibration and Resistance Exercise on Carotis Intima Media Thickness and Muscle Architecture in Patients With Hypertension

Forrás: ClinicalTrials.gov · Utoljára frissítve: 2025. ápr. 17.

Következő lépések

Rövid összefoglaló (regiszter, angolul)

Exercise is of great importance in the treatment of hypertension, which is expressed as a very serious disease, the prevalence of which is increasing day by day in the world and can cause many complications that are common in society. Exercise methods effective on carotid intima-media thickness, skeletal muscle architecture, and strength, which are important markers of hypertension-related organ damage, remain unclear. Strengthening exercises draw attention as an important approach in the control of hypertension. In order for strengthening exercises to be effective in the rehabilitation of hypertension, moderate and high-intensity exercises are recommended. New exercise approach strategies are gaining importance in order to enable resistance exercise training and to increase muscle mass and strength in the elderly who have a limitation for the recommended exercise intensity, in patients with hypertension, and in people with various diseases in which the cardiovascular system is affected. Whole body vibration (TVV) applications, which have no side effects reported as the current example of these exercise approaches, attract attention. Many positive effects occur on the cardiovascular system with the short-term and low-effort application of TVV exercise approaches, which are frequently used in routine rehabilitation practices. However, when the literature is examined, the effects of these exercise approaches on carotid intima-media thickness, which is one of the main markers of hypertension-related organ damage, are unclear. In addition, the effects of hypertension on quadriceps muscle architecture, which are expected to be adversely affected as a result of affecting autophagy regulation in skeletal muscle and causing decreased muscle capillarization, remain unclear. In addition, there is insufficient data on the effectiveness of strengthening exercises and TVV exercises on hemodynamic responses and quadriceps muscle strength in hypertensive patients. It will shed light on the determination of the exercise approach that is most effective on the muscle architecture, hemodynamic responses and carotid intima-media thickness of hypertensive patients and that can show these effects without overloading the cardiovascular system.

Állapot (regiszter)
Befejeződött
Vizsgálattípus
Beavatkozással járó
Résztvevők száma
43 (tényleges)
Első benyújtás
2023. febr. 13.
Kezdés
2023. febr. 10.
Elsődleges befejezés
2024. febr. 15.
Fő szponzor
Suleyman Demirel University
NCT-szám
NCT05775835

Mit vállalsz

  • Vizsgálat típusa: Beavatkozással járó
  • Bevont résztvevők: 43
  • 2023. febr. 10. és az elsődleges befejezés (2024. febr. 15.) között
  • 1 helyszín, 1 országban
  • Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket

A(z) ClinicalTrials.gov regisztermezőiből összeállítva. A vizsgálat felépítését írja le.

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Más betegség

  • Having any additional disease other than hypertension, such as diabetes mellitus, heart failure, unstable angina, myocardial infarction, kidney disease and psychiatric disease related to circulatory, orthopedic, neurological, cardiac and respiratory functions,
  • Hypertension-related medication change in the last 4 weeks

Egyéb

  • Using hormonal supplements,

Kiket keres a vizsgálat

  • Being between the ages of 30-59,
  • Being diagnosed with stable hypertension in stage 1 (systolic blood pressure 140-159 mmHg and diastolic blood pressure 90-99 mmHg) and stage 2 (systolic blood pressure 160-179 mmHg and diastolic blood pressure 100-109 mmHg),
  • Not being obese (BMI<30 kg/m2)
  • Not having the habit of exercise (regular exercise <60 min/week or not doing any strengthening exercise),
  • Not having a history of smoking,
  • Volunteering to participate in the study

Életkor a regiszterben: 30 év – 59 év · Nem: nők és férfiak · Egészséges önkénteseket nem fogad

A teljes feltétellista: ClinicalTrials.gov

Helyszínek (1)

Helyszínek a regiszter sorrendjében. Ha a profilodba mented a városodat, távolság szerint rendeződnek.

HelyszínVárosOrszágHelyszín állapota
Süleyman Demirel UniverstyIspartaTörökországIsmeretlen állapot

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