The Long-term Safety and Effect of Renal Denervation
Megadott ok: Guidewires used in the study are no longer manufactured
Key facts
- Where
- London, Egyesült KirályságSee the site
Where in Egyesült Királyság
- Hammersmith HospitalLondon, Egyesült KirályságNo longer taking part
Trial details
- Who runs it
- Imperial College Healthcare NHS Trust
- Trial code
- NCT05818813
- Record updated
- 2026. március 27.
- Original description
The goal of this observational study is to learn about the effects of renal denervation in patients with resistant hypertension. The main question it aims to answer is: What are the long term effects of renal denervation on blood pressure and flow within the arteries? Participants will undergo an assessment of their blood pressure, echocardiogram and invasive measurements of blood pressure and flow in the aorta and renal arteries before undergoing the renal denervation procedure. 6 months later these assessments will be repeated.Read full original descriptionShow less
The Long-term Safety and Effect of Renal Denervation for Resistant Hypertension
The goal of this observational study is to learn about the effects of renal denervation in patients with resistant hypertension. The main question it aims to answer is: What are the long term effects of renal denervation on blood pressure and flow within the arteries? Participants will undergo an assessment of their blood pressure, echocardiogram and invasive measurements of blood pressure and flow in the aorta and renal arteries before undergoing the renal denervation procedure. 6 months later these assessments will be repeated.
Inclusion: Systolic blood pressure >160mmHg despite 3 antihypertensive agents; eGFR >45.
Exclusion: Prior renal artery intervention; Secondary causes of hypertension; Renal insufficiency; Significant stenotic valvular heart disease; Myocardial infarction, unstable angina or stroke within the preceding 6 months.