Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma (TRIgnite-1)

Korábbi kezelés

• Uncontrolled infection requiring systemic antibiotic therapy or other serious infection prior to C1D1
• Any concurrent or uncontrolled medical, comorbid, psychiatric or social condition that would limit compliance with study procedures, interfere with the study results, substantially increase the risk of AEs, compromise ability to provide written informed consent or, in the opinion of the Investigator, constitute a hazard for participating in this study.

Más betegség

• Active malignant central nervous system involvement
• History of autoimmune disease requiring systemic immunosuppressive therapy

Egyéb

• Female subjects who are lactating and breastfeeding or have a positive pregnancy test during the screening period or on Day 1 before first dose of ISB 2001.

• Participants with pathologically confirmed MM with measurable M-protein: serum and/or 24 hour urine, serum-free light chains or measurable isolated plasmacytoma
• Have an Eastern Cooperative Oncology Group (ECOG) performance status score of 2 or less
• Must have adequate hematologic, hepatic, renal, and cardiac functions