Sauna for Long Covid

Korábbi kezelés

• Positive urine toxicology screen for illicit drug use
• Using medication that might impact thermoregulatory capacity and cannot be held for an appropriate length (at least one half-life) as determined by clinician judgment prior to receiving WBH treatment
• Breast Implants

Más betegség

• Fatigue for known reasons other than PASC (e.g. longstanding diagnosis of Chronic Fatigue Syndrome pre-dating Long Covid, low thyroid, multiple sclerosis, AIDS related fatigue, mononucleosis), as determined by clinical discretion of study investigators
• Known hypersensitivity to infrared heat exposure, significant history of heat stroke
• History of bipolar disorder, psychotic disorders, eating disorders, obsessive compulsive disorder, and/or substance use or dependence (within the last year), as per the Mini-International Neuropsychiatric Interview (MINI)44
• Any serious unstable medical condition
• Unsafe cardiac status as defined by abnormal ECG reading at screening visit or as determined by study doctor or subject's physician
• History of or current diagnosis of thrombosis or thrombophilia
• History of hemophilia
• History of febrile seizures or seizure disorders
• Any new treatments/medications for long-COVID that have started in the past 3 months

Egyéb

• Breastfeeding, pregnancy or planned pregnancy during study
• Active suicidal intent
• Inability to fit into the sauna device. Morbid obesity (BMI > 40) and/or body shape that might increase the risk of cutaneous burning from the device (because of skin being too close to the heat).
• Back pain that would interfere with ability to lay on hard surface
• Claustrophobia that would interfere with ability to remain in sauna
• A subject who in the opinion of the Principal Investigator would not be able to safely complete the study or would jeopardize study integrity.

• 18-65 years of age
• English language proficiency
• Ability to provide informed consent
• Ability to lie supine (on back) for 2 hours (required for sauna sessions)
• Must have had clinically suspected COVID-19 and a positive antibody test or a documented SARS-CoV-2 infection (a positive reverse transcription polymerase chain reaction test) at least 12 weeks prior to Screening (Note: clinician judgment can override lack of positive COVID test with clear Long Covid onset and presentation)
• The Patient Reported Outcome Measurement Information System Fatigue-Short Form v1.0 -Fatigue 7a (PROMIS F-SF43) raw score of 21 or greater at Screening (onset of fatigue confirmed post-infection as in other studies of PASC)
• Individuals of childbearing potential must use an acceptable form of birth control.