Added Value of a Neuroendocrine Test Battery in the Response to Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment

Korábbi kezelés

• Patient previously treated with monoamine oxidase inhibitor (MAOI) antidepressant or lithium salts (within 6 months prior to inclusion);

Más betegség

• Patient with a contraindication to neuroendocrine testing (hypersensitivity to the active substance or to one of the excipients);
• Patient with a contraindication to rTMS:
  • cochlear implant,
  • cardiac pacemaker,
  • metal clips, stents or other electronic implants within one meter of the stimulation coil,
  • intracranial hypertension,
  • poorly balanced comitiality,
  • in the case of well-balanced comitiality, a neurological consultation with electroencephalogram (EEG) is planned before including the patient;

Egyéb

• Patient with endocrinopathy ;
• Pregnant or lactating patient;
• Patient under court protection or deprived of liberty;
• Patient under guardianship/guardianship.

• Patient with a characterized depressive episode defined according to DSM-5 (diagnostic and statistical manual of mental disorders) criteria;
• Patient between the ages of 18 and 65 years;
• Inpatient with an inadequate response to two prior well-conducted antidepressant treatments (Hamilton 17-item scale \[HAMD-17\] score at inclusion≥ 18) ;
• Patient with written informed consent to participate in the study;
• Patient enrolled in or receiving social security benefits.