Feasibility of Improving Glycemia With Heat Therapy to Prevent AD

Korábbi kezelés

• ACSM Risk score stratification of "High" unless cleared by a physician prior to participation.

Más betegség

• Myocardial infarction or symptoms of coronary artery disease in the last 2 years.
• History of or current diagnosis of disorders with the potential to impair cognition (i.e. AD, Parkinson's disease, stroke (defined as clinical episode w/ neuroimaging evidence in appropriate area to explain symptoms)).
• Insulin-dependent (Type 1) Diabetes Mellitus.
• Clinically significant chronic disease such as cancer, HIV, or acquired immunodeficiency syndrome.
• Clinically significant depressive symptoms that may impair cognition, use of psychoactive and investigational medications, and significant visual or auditory impairment.
• Untreated hypothyroidism or diseases associated with heat intolerance (i.e. Graves disease, etc).
• Contraindication for temperature pill ingestion (i.e. inflammatory bowel disease, diverticulitis or related).

Laborértékek

• Excluded from or unable to complete an MRI scan. MRI compatible pacemakers will require cardiologist clearance prior to enrolling.

Egyéb

• Orthopedic complications that would preclude individuals from safely entering a hot tub.

• Age 65 and older
• Stable medication doses (>1 month)
• Post-menopausal
• Clinical Dementia Rating (CDR) of 0
• History of or current metabolic impairment (i.e. metabolic syndrome, pre-diabetes, Type 2 Diabetes, etc)