Comparison of Sublobar and Lobectomy in Small (2 Cm or Less 0.5<CTR<1) Non-small Cell Lung Cancer: a Prospective, Multicenter Randomized Controlled Study

Korábbi kezelés

• Those who have received anti-tumor treatment (radiotherapy, chemotherapy, Targeted therapy, immunotherapy) before surgery;
• Previous history of lung surgery;
• Those who undergo thoracotomy or change the surgical plan due to various reasons during surgery;
• Individuals who have conducted other clinical trials in the three months prior to enrollment.
  • Secondary exclusion criteria:

Más betegség

• Hypertension and diabetes difficult to control;
• Severe mental illness;
• Individuals with a history of severe heart disease, heart failure, myocardial infarction, or angina within the past 6 months;
• Active bacterial or fungal infections that are difficult to control;
• Postoperative pathological results of non NSCLC malignant tumors;
• Non small cell lung cancer confirmed histologically during operation, but with malignant Pleural effusion and pleural dissemination

Egyéb

• Initial exclusion criteria:
• Pregnant or lactating women;
• Interstitial pneumonia, Pulmonary fibrosis or severe Emphysema;
• The postoperative pathological result was Benign tumor;

• nitial inclusion criteria:
  • Age 18-75 years old, regardless of gender;
  • ECOG PS score 0-1 points (Attachment 3.4);
  • Preoperative clinical staging for patients with suspected NSCLC lesions in Phase I (according to AJCC Eighth Edition staging standards, Attachment 3.5);
  • Thin slice CT indicates that the maximum tumor diameter is ≤ 2.0cm;
  • Pre operative CT prompts 0.5<CTR<1.0;
  • Good lung function (FEV1>1.5 L or FEV1% ≥ 60%), able to tolerate both segmental resection and lobectomy;
  • The number of pulmonary nodules that need to be processed is ≤ 3, and the nodules are located in the same side of the lung;
  • Those who voluntarily sign the research informed consent form can comply with the research visit plan and other protocol requirements.