Study of Personalized Allocation of Defibrillators in Non-ischemic Heart Failure (SPANISH-1)

Más betegség

• History of coronary artery disease justifying the presence of ventricular dysfunction, defined as: history of coronary revascularisation or presence of significant coronary stenosis (≥50% in left main or ≥70% in a major epicardial artery) on invasive or non-invasive coronary angiography (coronary CT)
• Left ventricular dysfunction attributed to congenital heart disease, valvular disease, alcohol abuse or chemotherapy.
• History of recovered sudden death or sustained ventricular tachycardia.
• Waiting list for cardiac transplantation in emergency 0.
• Receiver of a solid organ transplant (lung, liver, heart or kidney).

Egyéb

• Hypertrophic or infiltrative cardiomyopathy, active myocarditis or constrictive pericarditis.
• NYHA functional class IV.

• Age ≥ 18 years at the time of screening.
• Previously established diagnosis of Non-ischemic DCM
• Optimised medical treatment at maximum tolerated doses for at least 3 months prior to the screening date.
• NYHA functional class II-III.
• LVEF ≤ 35% documented by CMR as study procedure.
• Life expectancy greater than 12 months.