A Study of Oral MBQ-167 in Participants With Advanced Breast Cancer

Korábbi kezelés

• Participants who have received any anticancer treatment within 4 weeks or any investigational agent within 28 days prior to the first dose of trial drug or who have not recovered from any acute toxicity greater than Grade 0 or 1 related to previous anticancer treatment.
• Participants who have received any anticancer treatment within 4 weeks or any investigational agent within 28 days prior to the first dose of trial drug or who have not recovered from any acute toxicity greater than Grade 0 or 1 related to previous anticancer treatment.

Más betegség

• Inability to take oral medication, or malabsorption syndrome or any other uncontrolled gastrointestinal condition (e.g., nausea, diarrhea, or vomiting) that might impair the bioavailability of MBQ-167.
• Active malignancies other than advanced breast cancer will be excluded from the study.

Egyéb

• The investigator will evaluate these and other criteria to determine whether a participant should be excluded from this study.
• Females who are pregnant or breastfeeding.

• The investigator will evaluate these and other criteria to determine whether a participant can be included in this study.
• Histologically and/or cytologically confirmed advanced breast cancer which has progressed after treatment with approved therapies or for which there are no standard therapies available.
• Participants with known brain metastases may be eligible if specific conditions are met.
• Life expectancy ≥6 months, in the opinion of the investigator, after starting MBQ-167.
• Are able to swallow capsules twice daily with a meal.