A Study to Evaluate the Safety and Efficacy of AK120 in Subjects With Moderate to Severe Atopic Dermatitis

Korábbi kezelés

• Received systemic corticosteroids, immunosuppressive/immunomodulatory drugs, phototherapy within the 4 weeks before randomization.
• Received systemic traditional Chinese medicine treatment within the 4 weeks before randomization or topical traditional Chinese medicine treatment within 1 week before randomization
• Received treatment with other clinical study drugs within 1 month or 5 half-lives before randomization (whichever is longer)
• Received or planned to receive live vaccine treatment within the 3 months before randomization or during the study period.
• Received allergen specific immunotherapy within the 3 months before randomization.

Más betegség

• Have a history of allergies to any component of AK120 and/or severe allergic reactions to monoclonal antibodies.

• Male or female subjects aged ≥18≤75 years old.
• Atopic dermatitis (AD) diagnosed at least half a year before screening.
• Subject with EASI score ≥16, IGA ≥ 3, BSA ≥ 10% at screening and baseline.
• Subjects with a history of an inadequate response or medically inappropriate use of topical drug treatment within 6 months