Association Between the Composition of the Intestinal Microbiota and Tumor Response in Locally Advanced Rectal Cancer
Megadott ok: Lack of eligible patients
Key facts
- Where
- Lille, FranciaországSee the site
Where in Franciaország
- Centre Oscar LambretLille, FranciaországNo longer taking part
Trial details
- Who runs it
- Centre Oscar Lambret
- Trial code
- NCT06181201
- Record updated
- 2026. március 18.
- Original description
This is an observational, single-centre study (RIPH3) for patients with rectal cancer soon to be treated with chemotherapy (+/- neo-adjuvant radio-chemotherapy) looking at the relationship between the composition of the gut microbiota before treatment and the tumour response after chemotherapy +/- radio-chemotherapyRead full original descriptionShow less
Association Between the Composition of the Intestinal Microbiota Before Treatment and the Tumor Response After Induction Chemotherapy Followed or Not by Neo-adjuvant Radio-chemotherapy in Locally Advanced Rectal Cancer
This is an observational, single-centre study (RIPH3) for patients with rectal cancer soon to be treated with chemotherapy (+/- neo-adjuvant radio-chemotherapy) looking at the relationship between the composition of the gut microbiota before treatment and the tumour response after chemotherapy +/- radio-chemotherapy
Inclusion: Histologically proven stage II and III adenocarcinoma of the lower and middle rectum; Patient undergoing preoperative treatment with induction chemotherapy (Folfirinox) followed or not by radio-chemotherapy of the Cap50 type; Male or female patient aged 18 years or older; Normal weight, overweight or moderately obese (BMI between 18.5 and 34.9); Patient residing in the Lille metropolitan area; Patient affiliated to a French social protection scheme; Patient having given his non-opposition.
Exclusion: History of other concurrent cancers; Presence of an intestinal (internal or external) or external urinary diversion; Uncooperative patient for geographical, family, social or psychological reasons; Limited legal capacity or legal incapacity.