The Effect of Lactobacillus Delbrueckii Subsp. Bulgaricus on Human's Weight Reduction

Korábbi kezelés

• Short-term use of steroids, NSAIDs, immunosuppressive drugs, interferons, immunomodulators, or any changes in the dose of long-term medications within the last month
• Use of any weight-loss drugs in the last three months (including Orlistat, Lorcaserin, and liraglutide)
• History of allergy to the investigational product

Más betegség

• History of diabetic ketoacidosis
• Medical records indicating the occurrence of cerebrovascular disease, acute myocardial infarction, coronary artery bypass surgery, placement of coronary artery stents, or peripheral vascular disease within the last 6 months
• Occurrence of acute infectious diseases within the last month and antibiotic use for > 7 days
• History of any cancer or undergoing cancer treatment in the past 5 years
• History of alcohol abuse

Laborértékek

• Impaired kidney function (eGFR < 30 mL/min/1.73 m2)

Egyéb

• Abnormal liver function (GOT or GPT greater than 3 times the normal upper limit) or liver cirrhosis
• Participation in any other interventional clinical research within the last month
• Pregnant and breastfeeding women
• Participants deemed unsuitable for inclusion by the principal investigator

• Age ≥ 20 years old
• Overweight (BMI ≥ 23) or body fat percentage ≥ 25% for males and ≥ 30% for females
• Having any of the following risk factors: Atherosclerotic cardiovascular disease, type 2 diabetes, age ≥ 45 years for males, ≥ 55 years for females or postmenopausal, hypertension, dyslipidemia (total cholesterol > 200 mg/dL or low-density lipoprotein cholesterol > 130 mg/dL or triglycerides > 130 mg/dL), high-density lipoprotein cholesterol < 40 mg/dL
• If routinely taking medication for lowering blood glucose, blood pressure, or lipid levels, there should not be significant dosage changes within the past three months
• Being willing to participate after receiving an explanation from the physician, completing the trial plan, and signing the consent form