Precision Adjuvant Therapy After Surgery for Hepatocellular Carcinoma

Korábbi kezelés

• A history of gastrointestinal bleeding within the previous 4 weeks or a definite predisposition to gastrointestinal bleeding (e.g., known locally active ulcer lesions, fecal occult blood ++ or more, or gastroscopy if persistent fecal occult blood +) that has not been targeted, or other conditions that may have caused gastrointestinal bleeding (e.g., severe fundoplication/esophageal varices), as determined by the investigator.

Más betegség

• Active infection.

Laborértékek

• Suffering from a condition that interferes with the absorption, distribution, metabolism, or clearance of the study drug (e.g., severe vomiting, chronic diarrhea, intestinal obstruction, impaired absorption, etc.).
• Other significant clinical and laboratory abnormalities that affect the safety evaluation.

Egyéb

• Pregnant and lactating women.
• Inability to follow the study protocol for treatment or follow up as scheduled.

• Aged 18-75.
• No previous local or systemic treatment for hepatocellular carcinoma.
• Child-Pugh liver function score ≤ 7.
• ECOG PS 0-1.
• No serious organic diseases of the heart, lungs, brain, kidneys, etc.
• Pathologic type is hepatocellular carcinoma.
• Confirmation of the presence of VETC vascular pattern by CD34 immunohistochemical staining.