Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients

Korábbi kezelés

• Use within 4 weeks of systemic treatment with immunosuppressive/immunomodulating drugs (corticosteroids, cyclosporine, mycophenolate, azathioprine, methotrexate)
• Treatment with biologics (dupilumab, omalizumab, benralizumab, etc) within sixteen weeks
• Use of topical steroids, topical calcineurin inhibitors within 7 days
• Asthmatics receiving more than 500 μg per day of inhaled corticosteroids

Más betegség

• Hypersensitivity to an agent used for the skin decolonization protocol
• History of (HIV, hepatitis B, hepatitis C, tuberculosis malignancy
• Severe ongoing medical illnesses e.g. cardiovascular, renal disease, autoimmune disease.
• Febrile illness at time of visits
• Suspected immune deficiency or family history of primary immunodeficiency

Egyéb

• . Enrollment in another clinical trial
• Phototherapy for AD within 4 weeks
• Bleach baths within 7 days of the first Visit
• Use of oral or topical antibiotics within 21 days of the beginning of the study
• Skin comorbidities that may interfere with assessments: psoriasis, cutaneous T Cell lymphoma,,
• Pregnancy

• Male or female participants ≥6 yrs of age
• Meet atopic dermatitis Standard Diagnostic Criteria
• SCORAD > 40.