A Study of Single and Multiple Doses HRS9531 Tablets in Healthy Subjects

Korábbi kezelés

• With previous major organ diseases, including but not limited to neuropsychiatric, cardiovascular, digestive, respiratory, urinary, endocrine, blood, immune and other diseases, are judged by researchers to be unsuitable for the study.
• Blood donation within 1 month prior to screening, or blood donation ≥400 mL or blood loss ≥400 mL within 3 months prior to screening.

Más betegség

• Known or suspected hypersensitivity to trial product(s) or related products.
• Hepatitis B surface antigen (HBsAg), HIV antibody detection, treponema pallidum specific antibody detection, hepatitis C virus antibody (HCVAb) positive.
• Known or suspected history of drug abuse or drug abuse, or urine drug screening test during the screening periodThose who are positive.
• In the opinion of the investigator, there are any other conditions that interfere with the evaluation of the results of the trial or are not suitable for participation of this study.

Egyéb

• Abnormal and clinically significant blood pressure at screening.
• Participation in other clinical trials.
• Presence of any clinically significant results in examination at screening visit.
• Presence of - clinically significant ECG results.
• Addiction to tobacco and alcohol.

• Ability to understand the trial procedures, be able and willing to provide a written informed consent.
• 18-55 years of age at the time of signing informed consent.
• SAD stage: Body weight ≥50 kg,19.0 ≤BMI≤ 35.0 kg/m2 at screening visit. MAD stage: 24.0 ≤BMI≤ 35.0 kg/m2 at screening visit.
• Subjects with good general health, no clinically significant abnormalities.