NCT06458153Toboroz
Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke
High-resolution Functional Imaging of Speech-induced Sensory Modulation
Forrás: ClinicalTrials.gov · Utoljára frissítve: 2026. jún. 18.
Rövid összefoglaló (regiszter, angolul)
The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes. The main questions it aims to answer are: 1. What regions of the brain's sensory systems show changes in their activity related to speech? 2. To what extent do these regions help listeners detect and correct speech errors? 3. What is the role of the cerebellum (a part of the brain in the back of the head) in these activities? Participants will be asked to complete several experimental sessions involving behavioral speech and related tests and non-invasive brain imaging using electroencephalography (EEG) and functional magnetic resonance imaging (fMRI).
- Állapot (regiszter)
- Toboroz
- Vizsgálattípus
- Beavatkozással járó
- Résztvevők száma
- 100 (tervezett)
- Első benyújtás
- 2024. jún. 3.
- Kezdés
- 2025. máj. 27.
- Elsődleges befejezés
- 2028. júl.
- Fő szponzor
- University of Pittsburgh
- Betegségek
- Stroke (szélütés)
- NCT-szám
- NCT06458153
Mit vállalsz
- Vizsgálat típusa: Beavatkozással járó
- Tervezett résztvevők: 100
- 2025. máj. 27. és az elsődleges befejezés (2028. júl.) között
- 1 helyszín, 1 országban
- Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket
A(z) ClinicalTrials.gov regisztermezőiből összeállítva. A vizsgálat felépítését írja le.
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Korábbi kezelés
- Presence of MRI risk factors: metal and/or electromagnetic devices (e.g., pacemakers, neurostimulators) in the body, previous shrapnel injuries, use of an intrauterine device containing metal, claustrophobia, pregnant or possibly pregnant
- Presence of MRI risk factors: metal and/or electromagnetic devices (e.g., pacemakers, neurostimulators) in the body, previous shrapnel injuries, use of an intrauterine device containing metal, claustrophobia, pregnant or possibly pregnant
- Presence of MRI risk factors: metal and/or electromagnetic devices (e.g., pacemakers, neurostimulators) in the body, previous shrapnel injuries, use of an intrauterine device containing metal, claustrophobia, pregnant or possibly pregnant
Más betegség
- History of neurological / neurodegenerative disease or severe brain injury (e.g., stroke or severe traumatic brain injury)
- Clinical diagnosis and/or treatment for schizophrenia or other psychotic disorders
- Clinical diagnosis and/or treatment for neurocognitive disorders (e.g., dementia, delirium)
- Presence of a severe and unmanaged, clinically diagnosed attention disorder
- Clinically diagnosed with or treated for a speech, language, or hearing disorder
- History of severe claustrophobia
- History of neurological / neurodegenerative disease or severe brain injury other than stroke
- Clinical diagnosis and/or treatment for schizophrenia or other psychotic disorders
- Clinical diagnosis and/or treatment for neurocognitive disorders (e.g., dementia, delirium)
- Presence of a severe and unmanaged, clinically diagnosed attention disorder
- History of severe claustrophobia
- History of neurological / neurodegenerative disease or severe brain injury (e.g., stroke or severe traumatic brain injury)
- Clinical diagnosis and/or treatment for schizophrenia or other psychotic disorders
- Clinical diagnosis and/or treatment for neurocognitive disorders (e.g., dementia, delirium)
- Presence of a severe and unmanaged, clinically diagnosed attention disorder
- Clinically diagnosed with or treated for a speech, language, or hearing disorder
- History of severe claustrophobia
Egyéb
- Cohort 1 (neurotypical adults):
- Hearing loss, defined by pure tone thresholds \>25 decibels (dB) hearing level (HL) at octave frequencies between 250-8000 Hz
- Head circumference greater than 60cm or weight greater than 300 pounds
- Currently pregnant
- Cohort 2 (people with cerebellar lesions):
- Hearing loss, defined by pure tone thresholds \>50 dB HL at octave frequencies between 250-4000 Hz
- Head circumference greater than 60cm or weight greater than 300 pounds
- Currently pregnant
- Cohort 3 (controls matched to Cohort 2):
- Hearing loss, defined by pure tone thresholds \>50 dB HL at octave frequencies between 250-4000 Hz
- Head circumference greater than 60cm or weight greater than 300 pounds
- Currently pregnant
Kiket keres a vizsgálat
- Cohort 1 (neurotypical adults):
- Age 18-49
- Right-handed
- Native English speaker
- Cohort 2 (people with cerebellar lesions):
- Age 18 or older
- Right-handed
- Native English speaker
- History of cerebellar stroke
- Cohort 3 (controls matched to Cohort 2)
- Age 18 or older
- Right-handed
- Native English speaker
Életkor a regiszterben: 18 év – - · Nem: nők és férfiak · Egészséges önkénteseket is fogad
Helyszínek (1)
Helyszínek a regiszter sorrendjében. Ha a profilodba mented a városodat, távolság szerint rendeződnek.
| Helyszín | Város | Ország | Helyszín állapota |
|---|---|---|---|
| University of Pittsburgh Ennek a helyszínnek vagy a koordinátora? Erősítsd meg az állapotát | Pittsburgh | Egyesült Államok | Toboroz |
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