A Multicenter, RAndomlzed, coNtrolled, umBrella Trial fOr Minimally Invasive Neurosurgery With Al-assisted Robotic guidanCe for Hemorrhagic Stroke: Large Basal Ganglia Hemorrhage

Korábbi kezelés

• Patients with concurrent severe illness likely to influence outcome assessment;

Más betegség

• Radiologically confirmed cerebral vascular abnormalities including ruptured aneurysms, arteriovenous malformations (AVMs), or Moyamoya disease; hemorrhagic transformation of ischemic infarcts; or recent (within 1 year) recurrence of intracerebral hemorrhage;

Laborértékek

• Any irreversible coagulation disorder or known coagulopathy; platelet count <100,000; INR >1.4; or use of anticoagulant medication within 7 days before the current hemorrhage;

Egyéb

• Hematoma involving the thalamus (volume >5 mL or diameter >2 cm), midbrain, or ventricles (Graeb score ≥3), or other locations;
• Signs of impending herniation such as midline shift exceeding 1 cm or ipsilateral pupillary changes;
• Current or probable pregnancy;
• Difficulty in follow-up or poor compliance due to any cause.

• Age ≥18 years at randomization;
• Diagnosed with hypertensive basal ganglia hemorrhage via imaging (CT, CTA, etc.);
• Hematoma volume ≥30 mL prior to randomization;
• Glasgow Coma Scale (GCS) score ≥ 5;
• Available for surgery within 72 hours after onset;
• Modified Rankin Scale (mRS) score ≤ 1 prior to this hemorrhage;
• Informed consent obtained in accordance with national laws, regulations, and applicable ethics committee requirements.