A Study to Evaluate the Impact of Long-term Digital Education vs Standard of Care on LDL-C Levels in Post Myocardial Infarction Patients

Korábbi kezelés

• History of previous myocardial infarction,
• History of previous coronary intervention due to ASCVD (percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG)),
• Patients treated with inclisiran prior to the hospitalization for myocardial infarction.

Más betegség

• History of ischemic stroke,
• Any surgical or medical condition, which in the opinion of the investigator, may place the participant at higher risk from his/her participation in the study, or is likely to prevent the participant from complying with the requirements of the study or completing the study,

Egyéb

• Participants meeting any of the following criteria are not eligible for inclusion in this study:
• Patients diagnosed with homozygous familial hypercholesterolemia,
• Unwillingness or inability (e.g., physical, or cognitive) to comply with study procedures (including adherence to study visits and fasting blood draws) and schedule,
• Participation in any other interventional study, both treatment and non-treatment interventional study,

• Participants eligible for inclusion in this study must fulfil all the following criteria:
• Male or female patients ≥18 years of age,
• At the Screening Visit, participants must be hospitalized for the first myocardial infarction. This must be a spontaneous MI (either ST-elevation MI or non-ST-elevation MI), which was not the result of percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG). Confirmation of MI is a combination of signs or symptoms consistent with presentation of MI, and at least one of the following (adapted from (Thygesen, et al., 2018)):
  • Documentation of cardiac biomarkers that exceed the diagnostic threshold of a local laboratory for MI
  • Pathological Q waves on ECG or other ECG changes as defined in Appendix 2
  • Imaging evidence of loss of viable myocardium or regional wall motion abnormality in a pattern consistent with an infarction or ischemic etiology
  • Identification of a coronary thrombus by angiography at the time of presentation with MI,
• LDL-C ≥ 1.8 mmol/L at the time of the hospitalization,
• Ability to participate in the hybrid educational program (must be able to receive emails and watch online educational videos),
• Patients must provide written consent to participate in the study.