NCT06740331Toboroz
Social Cognition, Memory, and Executive Functions in Bipolar Disorder and Major Depressive Disorder
Forrás: ClinicalTrials.gov · Utoljára frissítve: 2026. márc. 13.
Rövid összefoglaló (regiszter, angolul)
Bipolar disorder (BD) are common psychiatric disorders often misdiagnosed, leading to delayed treatment. Even during stable phases, individuals with bipolar disorder experience residual cognitive impairments that affect their social functioning and quality of life. This study aims to explore social cognition deficits (e.g., emotional processing, theory of mind, attribution bias) and their relationship with executive functions (e.g., flexibility, inhibition, working memory) and memory in bipolar disorder and major depressive disorder, ultimately seeking to improve understanding of their functional outcomes. Social cognition and executive functions in BD are both state- and trait-related. One recent meta-analysis demonstrated impairment in social cognitive domains for manic, depressive, and euthymic bipolar disorders' patients but it remains unclear whether these social cognitive deficits in BD are due to executive functions and/or other confounding effects. Few studies have investigated the interdependency between these cognitive impairments in these two affective disorders while a better understanding of the link between executive functions and social cognition seems crucial in order to better characterize the nature of patients' deficits and thus their caring.
- Állapot (regiszter)
- Toboroz
- Vizsgálattípus
- Beavatkozással járó
- Résztvevők száma
- 180 (tervezett)
- Első benyújtás
- 2024. dec. 13.
- Kezdés
- 2025. jan. 7.
- Elsődleges befejezés
- 2028. jan. 7.
- Fő szponzor
- CHU de Reims
- Betegségek
- Depresszió, Bipoláris zavar
- NCT-szám
- NCT06740331
Mit vállalsz
- Vizsgálat típusa: Beavatkozással járó
- Tervezett résztvevők: 180
- 2025. jan. 7. és az elsődleges befejezés (2028. jan. 7.) között
- 1 helyszín, 1 országban
- Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket
A(z) ClinicalTrials.gov regisztermezőiből összeállítva. A vizsgálat felépítését írja le.
Ki nem vehet részt
Szó szerint a(z) ClinicalTrials.gov forrásból, témák szerint csoportosítva. Hogy ki vehet részt, azt csak a vizsgálat csapata dönti el.
Más betegség
- The presence of any alcohol use disorder or any other substance use disorder in the last six months, except for tobacco dependence
- A significant general medical illness, including neurological disorders or head trauma
- A sensorial impairment uncorrected (visual and/or hearing)
- Group 3: First-degree relatives of bipolar patients
- A diagnosis of schizophrenia or of bipolar disorder or of depressive disorder according to DSM-5 criteria
- The presence of any alcohol use disorder or any other substance use disorder in the last six months, except for tobacco dependence
- A significant general medical illness, including neurological disorders or head trauma
- A sensorial impairment uncorrected (visual and/or hearing)
- Group 4, 5, 6: Healthy control participants
- A diagnosis of schizophrenia or of bipolar disorder or of major depressive disorder according to DSM-5 criteria
- The presence of any alcohol use disorder or any other substance use disorder in the last six months, except for tobacco dependence
- Participants having one first-degree relative presenting an bipolar disorder or depressive disorder or schizophrenia according to DSM-5 criteria
- A significant general medical illness, including neurological disorders or head trauma
- A sensorial impairment uncorrected (visual and/or hearing)
Kiket keres a vizsgálat
- Patients between 18 and 65 years old, men or women
- Having a diagnosis of bipolar disorder or depressive disorder
- No substantial change in treatment for 2 weeks preceding study enrollment
- Being a native French speaker
- Patients enrolled in the national healthcare insurance program
- Consenting to participate to the study
- Participants between 18 and 65 years old, men or women
- Participants having at least one first-degree relative presenting an bipolar disorder (parents, children, siblings)
- Being a native French speaker
- Patients enrolled in the national healthcare insurance program
- Consenting to participate to the study
- Participants between 18 and 65 years old, men or women
- Being a native French speaker
- Patients enrolled in the national healthcare insurance program
- Consenting to participate to the study
Életkor a regiszterben: 18 év – 65 év · Nem: nők és férfiak · Egészséges önkénteseket is fogad
Helyszínek (1)
Helyszínek a regiszter sorrendjében. Ha a profilodba mented a városodat, távolság szerint rendeződnek.
| Helyszín | Város | Ország | Helyszín állapota |
|---|---|---|---|
| CHU Reims Ennek a helyszínnek vagy a koordinátora? Erősítsd meg az állapotát | Reims | Franciaország | Toboroz |
Ez az oldal tájékoztatás, nem orvosi tanács. Bármely vizsgálatról az orvosoddal beszélj.