Építés alatt – nem éles oldal
Belépés

NCT06800586Toboroz

Tumors and Respiratory System Diseases Due to Air Pollution: New Biomarkers of Exposure and Effects

Forrás: ClinicalTrials.gov · Utoljára frissítve: 2025. dec. 19.

Következő lépések

Rövid összefoglaló (regiszter, angolul)

This study aims to examine the exposure to atmospheric pollutants in a group of non-smoking patients suffering from lung cancer, chronic obstructive pulmonary disease (COPD), and leukemia. The exposure to atmospheric pollutants will be assessed simultaneously in a group of healthy volunteers. The ultimate goal of the study is to enhance the understanding of the mechanisms by which atmospheric pollutants act, in order to develop new tools that can help halt or at least delay the development of diseases associated with pollution.

Állapot (regiszter)
Toboroz
Vizsgálattípus
Megfigyeléses
Résztvevők száma
300 (tervezett)
Első benyújtás
2024. nov. 28.
Kezdés
2025. szept. 15.
Elsődleges befejezés
2026. júl.
Fő szponzor
IRCCS Azienda Ospedaliero-Universitaria di Bologna
NCT-szám
NCT06800586

Mit vállalsz

  • Vizsgálat típusa: Megfigyeléses
  • Tervezett résztvevők: 300
  • 2025. szept. 15. és az elsődleges befejezés (2026. júl.) között
  • 3 helyszín, 1 országban
  • Vizitek és vizsgálatok: kérdezd a vizsgálat csapatát, a regiszter nem sorolja fel őket

A(z) ClinicalTrials.gov regisztermezőiből összeállítva. A vizsgálat felépítését írja le.

Ki nem vehet részt

Szó szerint a(z) ClinicalTrials.gov forrásból, témák szerint csoportosítva. Hogy ki vehet részt, azt csak a vizsgálat csapata dönti el.

Korábbi kezelés

  • Previous and/or current diagnosis of solid tumors, myelodysplastic syndromes, myeloproliferative neoplasms
  • Previous and/or current treatment with antineoplastic agents
    • Healthy Volunteer Cohort to be Recruited at the Department of Medical Oncology, IRCCS AOU of Bologna:
  • Previous diagnosis of solid tumors, myelodysplastic syndromes, myeloproliferative neoplasms
  • Previous treatment with antineoplastic agents (alkylating agents, hydroxyurea, topoisomerase II inhibitors, lenalidomide) -Presence of pre-existing genetic conditions (Fanconi anemia, ataxia- telangiectasia, Down syndrome, xeroderma pigmentosum, Li-Fraumeni syndrome)

Más betegség

  • Infection with human immunodeficiency virus (HIV), human T-lymphotropic virus types 1 or 2, or Epstein-Barr virus
    • Healthy Volunteer Cohort to be Recruited at the Hematology Department (Hospital-University Company, Policlinico Riuniti di Foggia):

Egyéb

  • Patient Cohort to be Recruited at the Department of Pneumology and Respiratory Intensive Care, IRCCS AOU of Bologna:
  • Deficiency of alpha-1 antitrypsin (A1AT)
    • Healthy Volunteer Cohort to be Recruited at the Department of Pneumology and Respiratory Intensive Care, IRCCS AOU of Bologna:
  • Workers from the Department of Pneumology and Respiratory Intensive Care, IRCCS AOU of Bologna, S. Orsola Polyclinic
    • Patient Cohort to be Recruited at the Department of Medical Oncology, IRCCS AOU of Bologna:
  • Workers from the Department of Medical Oncology, IRCCS AOU of Bologna, S. Orsola Polyclinic
    • Patient Cohort to be Recruited at the Hematology Department (Hospital-University Company, Policlinico Riuniti di Foggia):
  • Workers from the Hematology Department, Hospital-University Company, Policlinico Riuniti di Foggia

Kiket keres a vizsgálat

  • Patient Cohort to be Recruited at the Department of Pneumology and Respiratory Intensive Care, IRCCS AOU of Bologna:
  • Age ≥ 18 years
  • Patients with a diagnosis of COPD of any severity (FEV1/FVC < 0.7 after bronchodilation test)
  • Non-smokers according to ISS definition: patients who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
  • Signature of informed consent
    • Healthy Volunteer Cohort to be Recruited at the Department of Pneumology and Respiratory Intensive Care, IRCCS AOU of Bologna:
  • Age ≥ 18 years
  • Non-smokers according to ISS definition: subjects who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
  • Absence of comorbidities related to the study (COPD, solid tumors, leukemia) in medical history
  • Workers of the IRCCS AOU of Bologna, S. Orsola Polyclinic
  • Signature of informed consent
    • Patient Cohort to be Recruited at the Department of Medical Oncology, IRCCS AOU of Bologna:
  • Age ≥ 18 years
  • Patients with a diagnosis of lung neoplasm of any histotype and stage
  • Non-smokers according to ISS definition: patients who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
  • Signature of informed consent
    • Healthy Volunteer Cohort to be Recruited at the Department of Medical Oncology, IRCCS AOU of Bologna:
  • Age ≥ 18 years
  • Non-smokers according to ISS definition: subjects who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
  • Absence of comorbidities related to the study (COPD, solid tumors, leukemia) in medical history
  • Workers of the IRCCS AOU of Bologna, S. Orsola Polyclinic
  • Signature of informed consent
    • Patient Cohort to be Recruited at the Hematology Department (Hospital-University Company, Policlinico Riuniti di Foggia):
  • Age ≥ 18 years
  • Non-smokers according to ISS definition: patients who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
  • Patients with a diagnosis of leukemia of any type
  • Signature of informed consent
    • Healthy Volunteer Cohort to be Recruited at the Hematology Department (Hospital-University Company, Policlinico Riuniti di Foggia):
  • Age ≥ 18 years
  • Non-smokers according to ISS definition: subjects who declare having smoked less than 100 cigarettes (5 packs of 20) in their lifetime and are not currently smokers
  • Absence of comorbidities related to the study (COPD, solid tumors, leukemia) in medical history
  • Workers of the Hospital-University Company, Policlinico Riuniti di Foggia
  • Signature of informed consent

Életkor a regiszterben: 18 év – - · Nem: nők és férfiak · Egészséges önkénteseket is fogad

A teljes feltétellista: ClinicalTrials.gov

Helyszínek (3)

Helyszínek a regiszter sorrendjében. Ha a profilodba mented a városodat, távolság szerint rendeződnek.

HelyszínVárosOrszágHelyszín állapota
Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di BolognaBolognaOlaszországToboroz
Respiratory and Critical Care Unit, IRCCS Azienda Ospedaliera-Universitaria di BolognaBolognaOlaszországToboroz
Ematology Unit, Azienda Ospedaliero-Universitaria, Policlinico Riuniti di FoggiaFoggiaOlaszországToboroz

Te vagy a koordinátor? Erősítsd meg az adatokat

Ez az oldal tájékoztatás, nem orvosi tanács. Bármely vizsgálatról az orvosoddal beszélj.