Efficacy of Hi-tACS for Schizophrenia Negative Symptoms

Korábbi kezelés

• Alcohol or drug abuse/dependence;

Más betegség

• Meets DSM-5 diagnostic criteria for other mental disorders;
• Serious physical or central nervous system disease (intracranial infection, intracranial tumor, presence of metal objects in the skull; epilepsy, seizures; history of hydrocephalus or central nervous system tumors; with implanted electronic devices; serious cardiac disease and fitted with a pacemaker, etc.);
• Impaired skin integrity at the site of electrode placement or hypersensitivity to electrode gels or adhesives;
• Mental retardation (Wechsler Adult Intelligence Scale WAIS <70) and/or severe cognitive impairment (Brief Mental State Examination MMSE <24);
• Failure or refusal to sign the informed consent form.

Egyéb

• Total score ≥19 on the PANSS positive subscales (P1-P7) ;
• Severe negative symptoms that prevent the patient from completing the required assessments and interventions;
• Presence of vision and/or hearing problems that prevent completion of relevant tests;
• Pregnancy;
• Those who have participated or are participating in other clinical studies 3 months ago;

• Han Chinese population;
• Age ≥ 18 years;
• Education level ≥ 6 years, able to fill out questionnaires on their own, and having sufficient audiovisual level to complete the necessary examinations;
• Meets DSM-5 diagnostic criteria for schizophrenia as assessed by MINI 7.0;
• Residual negative symptoms, with at least one item ≥2 on the negative subscale of PANSS (N1-N7);
• Taking second-generation atypical antipsychotic medication, with no medication or dosage adjustments in the last two weeks
• Patients and guardians agreed to participate in the study and signed an informed consent form.