A Study of Eloralintide (LY3841136) in Chinese Participants With Obesity or Overweight

Korábbi kezelés

• Have any of the following abnormal blood pressure (BP) and/or pulse rate at screening, constituting a risk when taking the investigational product with minor deviations judged to be acceptable by the investigator:
  • Supine BP > 160/90 millimeter mercury (mmHg)
  • Supine pulse rate < 50 or > 100 beats per minute (bpm)
  • Orthostatic hypotension
• Have significant previous or current history of comorbidities capable of significantly altering the absorption, metabolism, or elimination of drugs
• Regularly use known drugs of abuse and/or show positive findings on drug screening that are not consistent with the medical history or concomitant medication history
• Have donated blood of more than 450 mL within the previous 3 months of study screening, or intend to donate blood during the course of the study

Más betegség

• Have known allergies to related compounds of eloralintide
• Have a history of chronic medical conditions involving the heart, liver, or kidneys
• Have a medical history or current evidence of clinically significant cardiac condition

Egyéb

• Are pregnant, or intend to become pregnant or to breastfeed during the study

• Chinese participants. To qualify as Chinese, all 4 of the participant's biological grandparents must be of exclusive Chinese descent and born in China
• Have had a stable body weight for 3 months prior to screening. Participants with body weight change of less than 5% will be allowed
• Have not modified diet or adopted any nutritional lifestyle modification for 3 months before randomization
• Have clinical laboratory test results within a normal range for the population or investigative site at screening and lead-in, or results with acceptable deviations that are judged to be not clinically significant by the investigator
• Have a body mass index (BMI) within the range 27 to 40 kilogram per square meter (kg/m²)