Posterior Mitral Isthmus Line With Vein of Marshall Ethanolisation Compared With Anterior Mitral Lines in Patients With Persistent Atrial Fibrillation

Korábbi kezelés

• Previous mitral line or any other left atrial ablation beyond pulmonary vein isolation
• Cardiac surgery within the previous 90 days.
• Percutaneous transluminal coronary angioplasty/stenting or myocardial infarction within the previous 30 days.
• Documented history of a thromboembolic event within the previous 60 days.

Más betegség

• Expecting cardiac transplantation or other cardiac surgery within 180 days.
• Significant restrictive, constrictive, or chronic obstructive pulmonary disease with chronic symptoms.
• Acute illness or active infection at time of index procedure
• Renal insufficiency
• Unstable angina.
• History of blood clotting or bleeding abnormalities.
• Uncontrolled heart failure.
• Presence of a condition that precludes vascular access.

Laborértékek

• Left ventricular ejection fraction \<25%.
• International normalised ratio (INR) greater than 4 within 24 hours of procedure - for patients taking warfarin.

Egyéb

• Left atrial (LA) thrombus. LA thrombus can be determined by preprocedural imaging: CT, transesophageal echocardiography or MRI.
• LA diameter greater than 60 mm on long axis parasternal view, or left atrial volume more than 250 cc.
• Diagnosed atrial myxoma.
• Significant congenital anomaly or medical problem that in the opinion of the investigator would preclude enrollment
• Women who are pregnant or who plan to become pregnant during the study.
• Contraindication to anticoagulation.
• Life expectancy less than 1 year.
• Unwilling or unable to provide informed consent.

• Patients between the ages of 18 and 80 years, diagnosed with symptomatic persistent AF with clinical indication for left atrial ablation with a mitral isthmus line. Pulmonary vein will be isolated in all patients before starting the mitral isthmus line (during a previous or the same procedure)