the MCCE vs EGD Trial

Más betegség

• History of active haematological disease including hemoglobinopathies such as thalassemia, Myelodysplastic syndromes, haematological malignancy, aplastic anaemia, or autoimmune haemolytic anaemia.
• Patients with known active gastrointestinal malignancy.
• Contraindications for CE: suspected or known gastrointestinal obstruction, stenosis, fistula, diverticula, presence of gastrointestinal obstruction symptoms such as pain or dysphagia; inoperative conditions or refusal to undergo abdominal surgery if required; history of laparotomy, gastric or bowel surgery; presence of metallic implants that is not MRI conditional.
• Contraindications for EGD: Possible gastrointestinal perforation, medically unstable patients, patient with known pharyngeal diverticulum, and patients with recent head and neck trauma.
• Inability to take 1-month DAPT such as non-deferrable surgery within 1 months, severe allergy or hypersensitivity reaction to aspirin or P2Y12 inhibitors, or patients in whom 1 months DAPT is not indicated.
• Patients who are in active heart failure or fluid-overload state.
• Patients who have chronic renal failure as defined by estimated glomerular filtration rate \<15 ml/min/1.73m2.

Egyéb

• Patients whose life-expectancy is less than 6 months.
• Patients who are pregnant or lactating.
• Patients who are unable to give informed consent.

• subjects are patients older than 18 years old with:
• the diagnosis of ACS as defined by symptoms of chest pain or shortness-of-breath, abnormal electrocardiogram and positive enzyme, requiring coronary intervention
• new-onset anaemia as defined by Hb\<11 g/dL on admission blood taking